Announcements Trials
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Phase

Phase 4 2Phase 2 2Phase NA 1Phase 3 1

Status

Unknown 3Completed 2Withdrawn 1

Sponsor Class

OTHER 5INDUSTRY 1

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6Breast 3

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 250Leukemia 186Lymphoma 137Leukemia, Myeloid, Acute 103Burkitt Lymphoma 90Myelodysplastic Syndromes 79Lymphoma, Non-Hodgkin 65Breast Neoplasms 60Lymphoma, Large B-Cell, Diffuse 59Leukemia, Lymphocytic, Chronic, B-Cell 49Lymphoma, Mantle-Cell 47Hodgkin Disease 47Graft vs Host Disease 46Lymphoma, Follicular 45Leukemia, Myeloid, Accelerated Phase 45Multiple Myeloma 39Leukemia, Myeloid, Chronic-Phase 39Congenital Abnormalities 39Myeloproliferative Disorders 38Blast Crisis 38Leukemia, Myelomonocytic, Chronic 37Leukemia, Biphenotypic, Acute 35Recurrence 34Lymphoma, Large-Cell, Immunoblastic 33Lymphoma, B-Cell, Marginal Zone 31Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 30Osteosarcoma 29Primary Myelofibrosis 27Neoplasms, Plasma Cell 25Leukemia, Myelogenous, Chronic, BCR-ABL Positive 25

Interventions

Pemetrexed 20Bevacizumab 10Radiotherapy 8Spinal Puncture 7osimertinib 6Methotrexate 6Magnetic Resonance Spectroscopy 6aflutinib 5Topotecan 5Specimen Handling 5Trastuzumab 4Temozolomide 4Radiotherapy, Intensity-Modulated 4Dexamethasone 3trastuzumab deruxtecan 2pembrolizumab 2paclitaxel-Angiopep-2 conjugate 2omburtamab I-131 2merphos 2lorlatinib 2aumolertinib 2WP 744 2Vitamin B 12 2Rituximab 2Radiation 2Folic Acid 2Drug Therapy 2Cytarabine 2Cyclophosphamide 2Capecitabine 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Meningeal Carcinomatosis × Methotrexate × Clear all
NCT03613181 2023-04-24

ANGLeD

Angiochem Inc

Phase 3 Unknown
150 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT04356222 2020-05-27

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Hebei Medical University

Phase 4 Unknown
30 enrolled
CNS

Meningeal Carcinomatosis

NCT00992602 2017-07-07

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

University of Washington

Phase 2 Completed
3 enrolled 8 charts
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT02590510 2016-10-28

Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis

Hebei Medical University

Phase 4 Unknown
50 enrolled
CNS

Meningeal Carcinomatosis

NCT01281696 2013-10-16

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

National Taiwan University Hospital

Phase 2 Completed
40 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT01438021 2012-11-09

Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease

City of Hope Medical Center

Phase NA Withdrawn
CNS

Meningeal Carcinomatosis

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