Announcements Trials
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Phase

Phase 4 2Phase 2 2Phase NA 1

Status

Unknown 2Completed 2Withdrawn 1

Sponsor Class

OTHER 5INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Breast 2

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 182Leukemia 128Lymphoma 91Leukemia, Myeloid, Acute 83Myelodysplastic Syndromes 64Burkitt Lymphoma 59Lymphoma, Non-Hodgkin 53Lymphoma, Large B-Cell, Diffuse 42Leukemia, Myeloid, Accelerated Phase 39Leukemia, Lymphocytic, Chronic, B-Cell 39Lymphoma, Mantle-Cell 38Hodgkin Disease 38Graft vs Host Disease 36Blast Crisis 35Congenital Abnormalities 34Multiple Myeloma 33Lymphoma, Follicular 33Leukemia, Myeloid, Chronic-Phase 33Myeloproliferative Disorders 32Recurrence 30Breast Neoplasms 29Leukemia, Myelomonocytic, Chronic 28Primary Myelofibrosis 26Lymphoma, Large-Cell, Immunoblastic 26Lymphoma, B-Cell, Marginal Zone 25Neoplasms, Plasma Cell 22Osteosarcoma 21Leukemia, Myelogenous, Chronic, BCR-ABL Positive 21Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 20Leukemia, Biphenotypic, Acute 20

Interventions

Pemetrexed 18Bevacizumab 9Spinal Puncture 7Radiotherapy 7Specimen Handling 5Methotrexate 5Magnetic Resonance Spectroscopy 5osimertinib 4aflutinib 4Trastuzumab 3Topotecan 3Temozolomide 3Dexamethasone 3trastuzumab deruxtecan 2pembrolizumab 2merphos 2lorlatinib 2Vitamin B 12 2Rituximab 2Radiotherapy, Intensity-Modulated 2Folic Acid 2Drug Therapy 2Cytarabine 2Cyclophosphamide 2tucatinib 1toripalimab 1sintilimab 1sacituzumab govitecan 1pertuzumab 1peginterferon alfa-2b 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
OTHER × Meningeal Carcinomatosis × Methotrexate × Clear all
NCT04356222 2020-05-27

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Hebei Medical University

Phase 4 Unknown
30 enrolled
CNS

Meningeal Carcinomatosis

NCT00992602 2017-07-07

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

University of Washington

Phase 2 Completed
3 enrolled 8 charts
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT02590510 2016-10-28

Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis

Hebei Medical University

Phase 4 Unknown
50 enrolled
CNS

Meningeal Carcinomatosis

NCT01281696 2013-10-16

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

National Taiwan University Hospital

Phase 2 Completed
40 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT01438021 2012-11-09

Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease

City of Hope Medical Center

Phase NA Withdrawn
CNS

Meningeal Carcinomatosis

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