Announcements Trials
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Phase

Phase 1 2

Status

Withdrawn 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Gastrointestinal 1Breast 1

Conditions

Glioblastoma 28Lung Neoplasms 13Gliosarcoma 13Carcinoma, Non-Small-Cell Lung 13Rectal Neoplasms 12Brain Neoplasms 11Squamous Cell Carcinoma of Head and Neck 10Sarcoma 9Prostatic Neoplasms 9Breast Neoplasms 9Astrocytoma 9Uterine Cervical Neoplasms 8Melanoma 8Glioma 8Esophageal Neoplasms 8Pancreatic Neoplasms 7Head and Neck Neoplasms 7Neoplasm Metastasis 5Lymphoma, Follicular 5Oropharyngeal Neoplasms 4Lymphoma, Mantle-Cell 4Leukemia, Lymphocytic, Chronic, B-Cell 4Carcinoma, Squamous Cell 4Stomach Neoplasms 3Ovarian Neoplasms 3Multiple Myeloma 3Mouth Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma, B-Cell, Marginal Zone 3Lymphoma, B-Cell 3

Interventions

Topotecan 3Radiotherapy 3Pemetrexed 3osimertinib 2WP 744 2Radiation 2Busulfan 2AZD3759 2tipifarnib 1sintilimab 1pembrolizumab 1peginterferon alfa-2b 1omburtamab I-131 1mafosfamide 1immunotoxin LMB-7 1gallium citrate 1azeliragon 1avelumab 1adavosertib 1Vitamin B 12 1Vinorelbine 1Trastuzumab 1Temozolomide 1Specimen Handling 1Rituximab 1Pentetic Acid 1Melphalan 1Magnetic Resonance Spectroscopy 1Interferons 1Immunotherapy, Adoptive 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Meningeal Carcinomatosis × Radiation × Clear all
NCT04460937 2026-04-29

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

National Cancer Institute (NCI)

Phase 1 Active not recruiting
4 enrolled 9 charts
CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

NCT06137651 2024-04-01

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Northwestern University

Phase 1 Withdrawn
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

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