Announcements Trials
Browse Landscape

Phase

Phase 1/2 3Phase 1 3Phase NA 1Phase 2 1

Status

Withdrawn 1Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Gastrointestinal 1Breast 1

Conditions

Glioblastoma 60Carcinoma, Non-Small-Cell Lung 48Lung Neoplasms 39Head and Neck Neoplasms 26Gliosarcoma 26Squamous Cell Carcinoma of Head and Neck 25Pancreatic Neoplasms 25Central Nervous System Neoplasms 23Brain Neoplasms 22Rectal Neoplasms 21Breast Neoplasms 17Astrocytoma 17Sarcoma 16Neoplasms 16Glioma 15Uterine Cervical Neoplasms 14Prostatic Neoplasms 14Esophageal Neoplasms 14Carcinoma, Squamous Cell 11Lymphoma, Follicular 10Leukemia 10Melanoma 9Lymphoma, Large B-Cell, Diffuse 9Lymphoma 9Leukemia, Lymphocytic, Chronic, B-Cell 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Lymphoma, Non-Hodgkin 8Neoplasm Metastasis 7Myelodysplastic Syndromes 7Lymphoma, Mantle-Cell 7

Interventions

Topotecan 3Radiotherapy 3Pemetrexed 3osimertinib 2WP 744 2Radiation 2Busulfan 2AZD3759 2tipifarnib 1sintilimab 1pembrolizumab 1peginterferon alfa-2b 1omburtamab I-131 1mafosfamide 1immunotoxin LMB-7 1gallium citrate 1azeliragon 1avelumab 1adavosertib 1Vitamin B 12 1Vinorelbine 1Trastuzumab 1Temozolomide 1Specimen Handling 1Rituximab 1Pentetic Acid 1Melphalan 1Magnetic Resonance Spectroscopy 1Interferons 1Immunotherapy, Adoptive 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Meningeal Carcinomatosis × Radiotherapy × Clear all
NCT06431685 2026-05-08

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Sichuan University

Phase 1 Recruiting
10 enrolled
CNS

Meningeal Carcinomatosis

NCT04460937 2026-04-29

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

National Cancer Institute (NCI)

Phase 1 Active not recruiting
4 enrolled 9 charts
CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

NCT06137651 2024-04-01

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Northwestern University

Phase 1 Withdrawn
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

Data powered by HemOnc (CC BY 4.0) Colophon âš¡