Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Completed 2Active not recruiting 2Withdrawn 1Unknown 1Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Gastrointestinal 1

Conditions

Prostatic Neoplasms 25Breast Neoplasms 21Glioblastoma 19Carcinoma, Non-Small-Cell Lung 17Sarcoma 11Squamous Cell Carcinoma of Head and Neck 10Lung Neoplasms 10Rectal Neoplasms 8Neoplasms 8Hodgkin Disease 8Head and Neck Neoplasms 8Brain Neoplasms 8Oropharyngeal Neoplasms 7Glioma 7Esophageal Squamous Cell Carcinoma 7Esophageal Neoplasms 7Uterine Cervical Neoplasms 6Pancreatic Neoplasms 6Astrocytoma 6Triple Negative Breast Neoplasms 5Lymphoma 5Colorectal Neoplasms 5Carcinoma, Squamous Cell 5Neoplasm Metastasis 4Melanoma 4Medulloblastoma 4Histiocytoma, Malignant Fibrous 4Small Cell Lung Carcinoma 3Rhabdomyosarcoma 3Recurrence 3

Interventions

Radiotherapy 2toripalimab 1pertuzumab 1lorlatinib 1azeliragon 1adavosertib 1Trastuzumab 1Radiation 1Pemetrexed 1Immunotherapy, Adoptive 1GDC-0084 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × Meningeal Carcinomatosis × Radiotherapy × Clear all
NCT04588545 2026-05-26

Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease

H. Lee Moffitt Cancer Center and Research Institute

Phase 1/2 Active not recruiting
33 enrolled
CNS

Meningeal Neoplasms, Meningeal Carcinomatosis

NCT04460937 2026-04-29

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

National Cancer Institute (NCI)

Phase 1 Active not recruiting
4 enrolled 9 charts
CNSGastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Brain Neoplasms, Meningeal Carcinomatosis

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