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Phase

Phase 2 1Phase 1/2 1

Status

Completed 2Active not recruiting 2Withdrawn 1Unknown 1Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Head and Neck Neoplasms 121Lung Neoplasms 119Glioblastoma 118Carcinoma, Non-Small-Cell Lung 118Breast Neoplasms 105Lymphoma 102Squamous Cell Carcinoma of Head and Neck 90Central Nervous System Neoplasms 83Prostatic Neoplasms 80Leukemia 77Pancreatic Neoplasms 67Gliosarcoma 66Rectal Neoplasms 63Precursor Cell Lymphoblastic Leukemia-Lymphoma 63Esophageal Neoplasms 63Brain Neoplasms 59Lymphoma, Large B-Cell, Diffuse 56Lymphoma, Follicular 55Lymphoma, Non-Hodgkin 49Hodgkin Disease 48Burkitt Lymphoma 46Sarcoma 43Lymphoma, Large-Cell, Immunoblastic 42Leukemia, Lymphocytic, Chronic, B-Cell 42Myelodysplastic Syndromes 37Lymphoma, Mantle-Cell 36Glioma 36Neoplasms 34Astrocytoma 34Lymphoma, B-Cell, Marginal Zone 33

Interventions

Pemetrexed 5Topotecan 3Dexamethasone 3Bevacizumab 3osimertinib 2Vitamin B 12 2Trastuzumab 2Spinal Puncture 2Radiotherapy 2Methotrexate 2Folic Acid 2Cytarabine 2Busulfan 2trioctyl phosphine oxide 1trastuzumab deruxtecan 1tipifarnib 1merphos 1mafosfamide 1immunotoxin LMB-7 1epothilone B 1avelumab 1aflutinib 1XL647 1Transplantation, Autologous 1Temozolomide 1Rituximab 1Referral and Consultation 1Radiotherapy, Intensity-Modulated 1Nivolumab 1Mental Status and Dementia Tests 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Meningeal Carcinomatosis × Radiotherapy × Clear all
NCT03507244 2019-12-26

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

The First Hospital of Jilin University

Phase 1/2 Completed
34 enrolled
CNS

Meningeal Carcinomatosis

NCT03082144 2019-08-01

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

The First Hospital of Jilin University

Phase 2 Completed
53 enrolled
CNS

Meningeal Carcinomatosis

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