Announcements Trials
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Phase

Phase 1 3Phase 2 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Ovarian Neoplasms 28Small Cell Lung Carcinoma 26Lung Neoplasms 20Neuroblastoma 17Carcinoma, Ovarian Epithelial 17Fallopian Tube Neoplasms 12Brain Neoplasms 10Uterine Cervical Neoplasms 8Sarcoma 8Leukemia 8Leukemia, Myeloid, Acute 6Central Nervous System Neoplasms 6Recurrence 5Medulloblastoma 5Lymphoma 5Gliosarcoma 5Glioblastoma 5Sarcoma, Ewing 4Rhabdoid Tumor 4Retinoblastoma 4Osteosarcoma 4Neuroectodermal Tumors, Primitive, Peripheral 4Neoplasms 4Burkitt Lymphoma 4Wilms Tumor 3Neoplasm Metastasis 3Myelodysplastic Syndromes 3Lymphoma, Non-Hodgkin 3Lymphoma, Large B-Cell, Diffuse 3Glioma 3

Interventions

Pemetrexed 5Bevacizumab 5osimertinib 3aflutinib 3Temozolomide 3trastuzumab deruxtecan 2Topotecan 2Spinal Puncture 2Specimen Handling 2Radiotherapy, Intensity-Modulated 2Methotrexate 2Magnetic Resonance Spectroscopy 2tucatinib 1trioctyl phosphine oxide 1pembrolizumab 1nimotuzumab 1merphos 1lenvatinib 1glutathione pegylated liposomal doxorubicin 1epothilone B 1envafolimab 1camrelizumab 1XL647 1Trastuzumab 1Transplantation, Autologous 1Radiotherapy 1Radiosurgery 1Nivolumab 1Mental Status and Dementia Tests 1Ipilimumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Meningeal Carcinomatosis × Topotecan × Clear all
NCT02684071 2020-01-10

Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

Nicklaus Children's Hospital f/k/a Miami Children's Hospital

Phase 2 Terminated
3 enrolled
CNS

Familial ependymoma, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Meningeal Carcinomatosis

NCT00005811 2013-02-21

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

National Cancer Institute (NCI)

Phase 2 Completed
77 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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