Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Completed 3Terminated 2

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1Other hematologic neoplasm 1Lymphoid 1

Conditions

Ovarian Neoplasms 55Small Cell Lung Carcinoma 39Lung Neoplasms 30Carcinoma, Ovarian Epithelial 29Neuroblastoma 25Fallopian Tube Neoplasms 23Uterine Cervical Neoplasms 18Neoplasms 18Leukemia 18Leukemia, Myeloid, Acute 14Precursor Cell Lymphoblastic Leukemia-Lymphoma 13Sarcoma 10Lymphoma 10Brain Neoplasms 9Recurrence 8Carcinoma, Non-Small-Cell Lung 8Unspecified Adult Solid Tumor, Protocol Specific 7Neoplasm Metastasis 7Myelodysplastic Syndromes 7Burkitt Lymphoma 7Blast Crisis 7Neuroectodermal Tumors, Primitive, Peripheral 6Lymphoma, Non-Hodgkin 6Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Follicular 6Leukemia, Myelomonocytic, Chronic 6Leukemia, Myelomonocytic, Acute 6Leukemia, Monocytic, Acute 6Leukemia, Megakaryoblastic, Acute 6Leukemia, Erythroblastic, Acute 6

Interventions

Pemetrexed 5Topotecan 3Dexamethasone 3Bevacizumab 3osimertinib 2Vitamin B 12 2Trastuzumab 2Spinal Puncture 2Radiotherapy 2Methotrexate 2Folic Acid 2Cytarabine 2Busulfan 2trioctyl phosphine oxide 1trastuzumab deruxtecan 1tipifarnib 1merphos 1mafosfamide 1immunotoxin LMB-7 1epothilone B 1avelumab 1aflutinib 1XL647 1Transplantation, Autologous 1Temozolomide 1Rituximab 1Referral and Consultation 1Radiotherapy, Intensity-Modulated 1Nivolumab 1Mental Status and Dementia Tests 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Meningeal Carcinomatosis × Topotecan × Clear all
NCT00005811 2013-02-21

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

National Cancer Institute (NCI)

Phase 2 Completed
77 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

NCT00025311 2012-11-09

Topotecan in Treating Patients With Recurrent, Progressive, or Refractory Cancer That is Metastatic to the Lining Around the Brain

NYU Langone Health

Phase 1 Completed
CNS

Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT00674674 2012-05-15

PBTC-019

Baylor College of Medicine

Phase 1 Completed
22 enrolled
CNS

Meningitis, Meningeal Carcinomatosis

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