Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Carcinoma, Non-Small-Cell Lung 129Melanoma 90Squamous Cell Carcinoma of Head and Neck 88Breast Neoplasms 70Triple Negative Breast Neoplasms 64Parkinson Disease 4, Autosomal Dominant Lewy Body 45Head and Neck Neoplasms 45Lung Neoplasms 38Ovarian Neoplasms 37Neoplasms 37Neoplasm Metastasis 37Colorectal Neoplasms 37Stomach Neoplasms 36Carcinoma, Renal Cell 34Carcinoma, Transitional Cell 31Pancreatic Neoplasms 29Urinary Bladder Neoplasms 28Carcinoma, Hepatocellular 27Recurrence 21Hodgkin Disease 21Uterine Cervical Neoplasms 20Endometrial Neoplasms 20Prostatic Neoplasms 18Esophageal Neoplasms 18Sarcoma 17Glioblastoma 17Brain Neoplasms 16Fallopian Tube Neoplasms 15Esophageal Squamous Cell Carcinoma 15Carcinoma, Squamous Cell 14

Interventions

Pemetrexed 5Bevacizumab 5osimertinib 3aflutinib 3Temozolomide 3trastuzumab deruxtecan 2Topotecan 2Spinal Puncture 2Specimen Handling 2Radiotherapy, Intensity-Modulated 2Methotrexate 2Magnetic Resonance Spectroscopy 2tucatinib 1trioctyl phosphine oxide 1pembrolizumab 1nimotuzumab 1merphos 1lenvatinib 1glutathione pegylated liposomal doxorubicin 1epothilone B 1envafolimab 1camrelizumab 1XL647 1Trastuzumab 1Transplantation, Autologous 1Radiotherapy 1Radiosurgery 1Nivolumab 1Mental Status and Dementia Tests 1Ipilimumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 2 × Meningeal Carcinomatosis × pembrolizumab × Clear all
NCT04729348 2025-07-25

Pembrolizumab And Lenvatinib In Leptomeningeal Metastases

Massachusetts General Hospital

Phase 2 Terminated
10 enrolled
CNS

Meningeal Carcinomatosis

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