Clinical Trials Browser

Phase 2 × Completed × Meningeal Carcinomatosis × Clear all

NCT06812871 2026-04-02

High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal Metastasis

Phase 2 Completed

Meningeal Carcinomatosis

NCT04343573 2026-02-27

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

Phase 2 Completed

Meningeal Carcinomatosis

NCT02939300 2025-11-14

Ipilimumab and Nivolumab in Leptomeningeal Metastases

Phase 2 Completed

18 enrolled 17 charts

Meningeal Carcinomatosis

NCT04420598 2025-06-24

DEBBRAH

Phase 2 Completed

41 enrolled 32 charts

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT04233021 2025-02-03

ORBITAL

Phase 2 Completed

Brain Neoplasms, Meningeal Carcinomatosis

NCT05146219 2024-12-30

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

Phase 2 Completed

Brain Neoplasms, Meningeal Carcinomatosis

NCT00801216 2024-12-10

SCNSL1

Phase 2 Completed

40 enrolled 11 charts

Lymphoma, B-Cell, Meningeal Carcinomatosis

NCT02616393 2022-03-16

Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases

Phase 2 Completed

36 enrolled 22 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT03082144 2019-08-01

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Phase 2 Completed

Meningeal Carcinomatosis

NCT00992602 2017-07-07

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Phase 2 Completed

3 enrolled 8 charts

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT02654106 2017-06-06

SRTRBM

Phase 2 Completed

Brain Neoplasms, Meningeal Carcinomatosis

NCT00450866 2014-02-28

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Phase 2 Completed

55 enrolled 12 charts

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male, Meningeal Carcinomatosis

NCT01281696 2013-10-16

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

Phase 2 Completed

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT00005811 2013-02-21

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Phase 2 Completed

CNSLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Medulloblastoma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis