Announcements Trials
Browse Landscape

Phase

Phase 2 33Phase 1 25Phase NA 16Phase 1/2 13Phase 4 6Phase 3 2Phase EARLY_PHASE1 1

Status

Unknown 3Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6Thoracic 1

Conditions

Breast Neoplasms 207Neoplasms 130Polycystic Ovary Syndrome 107Carcinoma, Hepatocellular 82Colorectal Neoplasms 77Prostatic Neoplasms 70Stomach Neoplasms 55Lung Neoplasms 51Precursor Cell Lymphoblastic Leukemia-Lymphoma 49Carcinoma, Non-Small-Cell Lung 43Pancreatic Neoplasms 41Pain, Postoperative 41Head and Neck Neoplasms 38Pain 37Liver Neoplasms 36Leukemia, Myeloid, Acute 32Leiomyoma 32Keratosis, Actinic 31Colonic Neoplasms 31Recurrence 30Neoplasm Metastasis 29Multiple Myeloma 28Infertility 28Brain Neoplasms 28Uterine Cervical Neoplasms 26Urinary Bladder Neoplasms 24Ovarian Neoplasms 24Lymphoma 24Esophageal Neoplasms 23Obesity 22

Interventions

Methotrexate 2lorlatinib 1durvalumab 1Endostatins 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 4 × OTHER × Meningeal Carcinomatosis × Clear all
NCT06282874 2026-04-09

Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

Guangdong Association of Clinical Trials

Phase 4 Active not recruiting
41 enrolled
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT06230055 2025-11-25

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Fudan University

Phase 4 Recruiting
37 enrolled
CNS

Meningeal Carcinomatosis

NCT07092202 2025-07-29

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 4 Recruiting
40 enrolled
CNS

Meningeal Carcinomatosis

NCT04356118 2020-05-27

Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Hebei Medical University

Phase 4 Unknown
30 enrolled
CNS

Meningeal Carcinomatosis

NCT04356222 2020-05-27

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Hebei Medical University

Phase 4 Unknown
30 enrolled
CNS

Meningeal Carcinomatosis

NCT02590510 2016-10-28

Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis

Hebei Medical University

Phase 4 Unknown
50 enrolled
CNS

Meningeal Carcinomatosis

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