Announcements Trials
Browse Landscape

Phase

Phase 2 40Phase 1 38Phase NA 21Phase 1/2 15Phase 4 6Phase 3 3Phase EARLY_PHASE1 1Phase 2/3 1

Status

Unknown 3Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6Thoracic 1

Conditions

Breast Neoplasms 276Neoplasms 202Prostatic Neoplasms 118Polycystic Ovary Syndrome 114Colorectal Neoplasms 104Carcinoma, Hepatocellular 103Carcinoma, Non-Small-Cell Lung 88Lung Neoplasms 70Stomach Neoplasms 62Precursor Cell Lymphoblastic Leukemia-Lymphoma 60Pain 59Neoplasm Metastasis 54Multiple Myeloma 52Pancreatic Neoplasms 46Keratosis, Actinic 46Head and Neck Neoplasms 43Pain, Postoperative 42Leukemia, Myeloid, Acute 40Leiomyoma 39Recurrence 38Liver Neoplasms 38Colonic Neoplasms 37Uterine Cervical Neoplasms 35Lymphoma 35Brain Neoplasms 34Infertility 33Papillomavirus Infections 32Ovarian Neoplasms 31Lymphoma, Follicular 31Lymphoma, Non-Hodgkin 30

Interventions

Methotrexate 2lorlatinib 1durvalumab 1Endostatins 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 4 × Interventional × Meningeal Carcinomatosis × Clear all
NCT06282874 2026-04-09

Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

Guangdong Association of Clinical Trials

Phase 4 Active not recruiting
41 enrolled
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT06230055 2025-11-25

Intrathecal Chemotherapy Through Ommaya Reservoir Upon Her-2 Negative Breast Cancer With Leptomeningeal Metastasis

Fudan University

Phase 4 Recruiting
37 enrolled
CNS

Meningeal Carcinomatosis

NCT07092202 2025-07-29

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Phase 4 Recruiting
40 enrolled
CNS

Meningeal Carcinomatosis

NCT04356118 2020-05-27

Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Hebei Medical University

Phase 4 Unknown
30 enrolled
CNS

Meningeal Carcinomatosis

NCT04356222 2020-05-27

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Hebei Medical University

Phase 4 Unknown
30 enrolled
CNS

Meningeal Carcinomatosis

NCT02590510 2016-10-28

Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis

Hebei Medical University

Phase 4 Unknown
50 enrolled
CNS

Meningeal Carcinomatosis

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