Announcements Trials
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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Carcinoma, Transitional Cell 16Urinary Bladder Neoplasms 15Carcinoma, Merkel Cell 10Neoplasm Metastasis 8Carcinoma, Renal Cell 8Breast Neoplasms 8Neoplasms 6Triple Negative Breast Neoplasms 5Melanoma 5Ureteral Neoplasms 4Stomach Neoplasms 4Squamous Cell Carcinoma of Head and Neck 4Ovarian Neoplasms 4Carcinoma, Non-Small-Cell Lung 4Uterine Cervical Neoplasms 3Urethral Neoplasms 3Skin Neoplasms 3Prostatic Neoplasms 3Colorectal Neoplasms 3Small Cell Lung Carcinoma 2Sarcoma 2Neuroendocrine Tumors 2Head and Neck Neoplasms 2Endometrial Neoplasms 2Carcinoma, Squamous Cell 2Carcinoma, Hepatocellular 2Uveal Melanoma 1Urothelial Cancer 1Turcot syndrome 1Thymoma 1

Interventions

Trastuzumab 4tucatinib 3Capecitabine 3fludarabine 2Radiotherapy 2Magnetic Resonance Spectroscopy 2Cyclophosphamide 2sapanisertib 1pertuzumab 1patritumab deruxtecan 1omburtamab I-131 1gadopiclenol 1gadobutrol 1fludarabine phosphate 1avelumab 1aldesleukin 1Spinal Puncture 1Specimen Handling 1Nivolumab 1Methotrexate 1Mesna 1Interleukin-2 1Blood Specimen Collection 1AZD1390 1

Date Range

30 days90 days1 yearAll

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Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Meningeal Neoplasms × avelumab × 1 year × Clear all
NCT03719768 2026-03-02

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
16 enrolled
CNS

Brain Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

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