Announcements Trials
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Phase

Phase 2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Breast 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 26Burkitt Lymphoma 21Leukemia, Biphenotypic, Acute 13Leukemia, Myeloid, Acute 8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 6Leukemia 5Osteosarcoma 4Myelodysplastic Syndromes 4Leukemia, Myeloid, Accelerated Phase 4Blast Crisis 4Recurrence 3Neoplasm Metastasis 3Myeloproliferative Disorders 3Lymphoma, Mantle-Cell 3Lymphoma 3Down Syndrome 3Blastic Plasmacytoid Dendritic Cell Neoplasm 3Rhabdoid Tumor 2Multiple Myeloma 2Lymphoma, Non-Hodgkin 2Leukemia, Myelomonocytic, Juvenile 2Hemoglobinuria, Paroxysmal 2Head and Neck Neoplasms 2Anemia, Refractory, with Excess of Blasts 2Waldenstrom Macroglobulinemia 1Urothelial Carcinoma of the Bladder 1Urinary Bladder Neoplasms 1Thrombocythemia, Essential 1Squamous Cell Carcinoma of Head and Neck 1

Interventions

Magnetic Resonance Spectroscopy 2sapanisertib 1pertuzumab 1patritumab deruxtecan 1gadopiclenol 1gadobutrol 1fludarabine phosphate 1fludarabine 1aldesleukin 1Trastuzumab 1Spinal Puncture 1Specimen Handling 1Radiotherapy 1Nivolumab 1Methotrexate 1Mesna 1Interleukin-2 1Cyclophosphamide 1Blood Specimen Collection 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Meningeal Neoplasms × Methotrexate × 90 days × Clear all
NCT02422641 2026-06-01

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

Wake Forest University Health Sciences

Phase 2 Recruiting
16 enrolled
Breast

Breast Neoplasms, Meningeal Neoplasms

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