Announcements Trials
Browse Landscape

Phase

Phase 1 4Phase 4 1Phase 2 1

Status

Recruiting 10Completed 6Terminated 5Active not recruiting 5Not yet recruiting 2Unknown 1

Sponsor Class

OTHER 3NIH 2INDUSTRY 1

Study Type

Interventional 6Observational 1

Sponsor

Cancer Type

Other hematologic neoplasm 3Lymphoid 3CNS 2Breast 1

Conditions

Breast Neoplasms 5004Neoplasms 4197Prostatic Neoplasms 2428Carcinoma, Non-Small-Cell Lung 2265Colorectal Neoplasms 2053Lung Neoplasms 1705Multiple Myeloma 1459Lymphoma 1405Leukemia, Myeloid, Acute 1382Neoplasm Metastasis 1374Melanoma 1270Pancreatic Neoplasms 1200Leukemia 1196Ovarian Neoplasms 1192Lymphoma, Non-Hodgkin 1132Precursor Cell Lymphoblastic Leukemia-Lymphoma 1091Head and Neck Neoplasms 1056Leukemia, Lymphocytic, Chronic, B-Cell 994Lymphoma, Follicular 897Colonic Neoplasms 895Brain Neoplasms 876Stomach Neoplasms 857Recurrence 853Carcinoma, Hepatocellular 846Glioblastoma 841Lymphoma, Large B-Cell, Diffuse 771Rectal Neoplasms 759Uterine Cervical Neoplasms 728Carcinoma, Renal Cell 705Hodgkin Disease 698

Interventions

patritumab deruxtecan 1mafosfamide 1avelumab 1Topotecan 1Cytarabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Interventional × Meningeal Neoplasms × Clear all
NCT05865990 2026-05-04

TUXEDO-3

MedSIR

Phase 2 Completed
63 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms

NCT03719768 2026-03-02

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
16 enrolled
CNS

Brain Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT00062881 2020-03-04

Intrathecal Mafosfamide

Baylor College of Medicine

Phase 1 Completed
65 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Meningeal Neoplasms, Neoplasms

NCT00001251 2013-08-19

Phase I Study of Intrathecal Mafosfamide

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
65 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Meningeal Neoplasms

NCT00001333 2008-03-04

Phase I Study of Intrathecal Topotecan

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
30 enrolled
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Meningeal Neoplasms

NCT00029523 2007-02-28

DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor

Pacira Pharmaceuticals, Inc

Phase 4 Completed
100 enrolled

Meningeal Neoplasms, Meningitis

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