Announcements Trials
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Phase

Phase 1/2 2Phase 3 1Phase 1 1

Status

Active not recruiting 3Terminated 1

Sponsor Class

NIH 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Other solid neoplasm 4

Conditions

Uterine Cervical Neoplasms 9Squamous Cell Carcinoma of Head and Neck 7Carcinoma, Non-Small-Cell Lung 6Lung Neoplasms 5Urinary Bladder Neoplasms 4Mesothelioma, Malignant 4Urethral Neoplasms 3Small Cell Lung Carcinoma 3Oropharyngeal Neoplasms 3Neuroblastoma 3Medulloblastoma 3Ganglioneuroblastoma 3Cholangiocarcinoma 3Vulvar Neoplasms 2Vaginal Neoplasms 2Ureteral Neoplasms 2Tongue Neoplasms 2Prostatic Neoplasms 2Lymphoid Interstitial Pneumonia 2Laryngeal Neoplasms 2Gallbladder Neoplasms 2Carcinoma, Transitional Cell 2Brenner Tumor 2Vomiting 1Triple Negative Breast Neoplasms 1Stomach Neoplasms 1Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 1Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 1Solitary Fibrous Tumor, Pleural 1Sertoli-Leydig Cell Tumor 1

Interventions

Pemetrexed 15Cisplatin 13pembrolizumab 6Platinum 41,2-diaminocyclohexaneplatinum II citrate 4cediranib 3Radiotherapy 3Gemcitabine 3Carboplatin 3amatuximab 2Radiotherapy, Intensity-Modulated 2Radiation 2Everolimus 2Drug Therapy 2Cyclophosphamide 2tumor necrosis factor-alpha, CNGRC fusion protein, human 1tremelimumab 1sodium thiosulfate 1sargramostim 1nintedanib 1napabucasin 1methoxyamine 1liposomal doxorubicin 1incomplete Freund's adjuvant 1fresolimumab 1durvalumab 1defactinib 1cixutumumab 1bintrafusp alfa protein, human 1bemcentinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Has results × Mesothelioma, Malignant × 1,2-diaminocyclohexaneplatinum II citrate × Clear all
NCT01064648 2026-05-29

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

National Cancer Institute (NCI)

Phase 1/2 Active not recruiting
117 enrolled 23 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT03228537 2026-05-29

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

National Cancer Institute (NCI)

Phase 1 Active not recruiting
28 enrolled 17 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT04158141 2026-05-19

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

NRG Oncology

Phase 3 Terminated
16 enrolled 18 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT02535312 2026-04-17

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

National Cancer Institute (NCI)

Phase 1/2 Active not recruiting
30 enrolled 15 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant

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