Announcements Trials
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Phase

Phase 1/2 2Phase 1 2

Status

Completed 21Terminated 9Withdrawn 4Recruiting 4Active not recruiting 4Unknown 3Not yet recruiting 1

Sponsor Class

NIH 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Other solid neoplasm 4

Conditions

Carcinoma, Non-Small-Cell Lung 68Lung Neoplasms 18Neoplasms 7Neoplasm Metastasis 7Melanoma 5Carcinoma 5Parkinson Disease 4, Autosomal Dominant Lewy Body 4Mesothelioma, Malignant 4Colorectal Neoplasms 4Ovarian Neoplasms 3Carcinoma, Transitional Cell 3Squamous Cell Carcinoma of Head and Neck 2Pancreatic Neoplasms 2Non-Squamous Non-small Cell Lung Cancer 2Non-Small Cell Lung Cancer Metastatic 2Non Small Cell Lung Carcinoma NSCLC 2Mesothelioma 2Endometrial Neoplasms 2Brain Neoplasms 2Advanced Solid Tumors 2Uveal Melanoma 1Uterine Cervical Neoplasms 1Stomach Neoplasms 1Solitary Fibrous Tumor, Pleural 1Salivary Gland Neoplasms 1Resectable Stage IIA to IIIB Non-small Cell Lung Cancer 1Resectable Non-small Cell Lung Cancer 1Recurrent Metastatic Non-Squamous Non Small Cell Lung Cancer 1Rectal Neoplasms 1Primary Myelofibrosis 1

Interventions

pembrolizumab 5Cisplatin 5Platinum 4Pemetrexed 41,2-diaminocyclohexaneplatinum II citrate 4Nivolumab 3Cyclophosphamide 3fludarabine 2atezolizumab 2Ipilimumab 2Carboplatin 2tremelimumab 1sargramostim 1methoxyamine 1lenvatinib 1cediranib 1anetumab ravtansine 1UV1 vaccine 1Radiotherapy, Intensity-Modulated 1Radiotherapy 1Radiation 1Interleukin-2 1Imprint II 1Immunotherapy, Adoptive 1Immunoglobulin G 1Gemcitabine 1Disulfides 1Bevacizumab 1BAY 1895344 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Active not recruiting × Mesothelioma, Malignant × Pemetrexed × Clear all
NCT01064648 2026-05-29

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

National Cancer Institute (NCI)

Phase 1/2 Active not recruiting
117 enrolled 23 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT03228537 2026-05-29

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

National Cancer Institute (NCI)

Phase 1 Active not recruiting
28 enrolled 17 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02535312 2026-04-17

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

National Cancer Institute (NCI)

Phase 1/2 Active not recruiting
30 enrolled 15 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT04162015 2025-09-12

A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

Memorial Sloan Kettering Cancer Center

Phase 1 Active not recruiting
22 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

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