Announcements Trials
Browse Landscape

Phase

Phase 2 8Phase 1 6Phase 1/2 4

Status

Active not recruiting 2Withdrawn 1Terminated 1Recruiting 1Completed 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 6Other solid neoplasm 6

Conditions

Carcinoma, Non-Small-Cell Lung 126Melanoma 92Neoplasms 82Colorectal Neoplasms 62Squamous Cell Carcinoma of Head and Neck 61Neoplasm Metastasis 59Triple Negative Breast Neoplasms 51Carcinoma, Renal Cell 47Breast Neoplasms 39Lung Neoplasms 37Ovarian Neoplasms 32Pancreatic Neoplasms 30Head and Neck Neoplasms 29Stomach Neoplasms 28Urinary Bladder Neoplasms 26Carcinoma, Transitional Cell 26Endometrial Neoplasms 24Parkinson Disease 4, Autosomal Dominant Lewy Body 23Uterine Cervical Neoplasms 21Carcinoma, Hepatocellular 18Recurrence 15Esophageal Neoplasms 15Prostatic Neoplasms 14Lymphoma 14Small Cell Lung Carcinoma 12Carcinoma, Squamous Cell 12Kidney Neoplasms 11Cholangiocarcinoma 11Advanced Solid Tumor 11Solid Tumor 10

Interventions

Cisplatin 14Pemetrexed 11pembrolizumab 6Cyclophosphamide 6Radiotherapy 3Interleukin-2 3Gemcitabine 3sodium thiosulfate 2sargramostim 2defactinib 2aldesleukin 2Surgical Procedures, Operative 2SS1(dsFv)PE38 2Radiation 2Platinum 2Pharmaceutical Preparations 2Paclitaxel 2Nivolumab 2Drug Therapy 2Depsipeptides 2Decitabine 2Celecoxib 2Carboplatin 21,2-diaminocyclohexaneplatinum II citrate 2osimertinib 1incomplete Freund's adjuvant 1entinostat 1cabozantinib 1bemcentinib 1atezolizumab 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 1 × Mesothelioma, Malignant × pembrolizumab × Clear all
NCT02959463 2026-05-27

Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma

M.D. Anderson Cancer Center

Phase 1 Completed
25 enrolled 11 charts
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT04897022 2026-03-12

A Study of Pembrolizumab and Radiation Therapy in People With Mesothelioma

Memorial Sloan Kettering Cancer Center

Phase 1 Active not recruiting
7 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT03760575 2025-12-04

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

Abramson Cancer Center at Penn Medicine

Phase 1 Recruiting
20 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT03546426 2024-10-01

MESOVAX

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS

Phase 1 Active not recruiting
18 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant, Disease Progression

NCT02707666 2024-07-31

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

University of Chicago

Phase 1 Terminated
7 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT04201145 2020-11-17

Pembrolizumab + Defactinib In Pleural Mesothelioma

Dana-Farber Cancer Institute

Phase 1 Withdrawn
Other solid neoplasmThoracic

Mesothelioma, Malignant

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