Clinical Trials

9 enrolled

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Pleural Diseases

NCT03420963 2026-03-20

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Terminated

12 enrolled

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT04897022 2026-03-12

A Study of Pembrolizumab and Radiation Therapy in People With Mesothelioma

7 enrolled

Mesothelioma, Malignant

NCT02959463 2026-03-06

Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma

24 enrolled 11 charts

Mesothelioma, Malignant

NCT07192900 2026-01-15

(RIOT 4A)

Phase 1 Recruiting

Mesothelioma, Malignant, Pleural Effusion, Malignant

NCT03760575 2025-12-04

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

Phase 1 Recruiting

20 enrolled

Mesothelioma, Malignant

NCT04162015 2025-09-12

A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

22 enrolled

Mesothelioma, Malignant

NCT04577326 2025-07-25

Mesothelin-targeted CAR T-cell Therapy in Patients With Mesothelioma

14 enrolled

Mesothelioma, Malignant

NCT04040231 2025-05-13

Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma

GenitourinaryOther solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma, Wilms Tumor

NCT03054298 2025-04-29

CAR T Cells in Mesothelin Expressing Cancers

GynecologicOther solid neoplasmThoracic

65 enrolled 14 charts

Adenocarcinoma of Lung, Mesothelioma, Malignant, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT05304208 2025-04-25

ENSURE

Phase 1 Recruiting

16 enrolled

Mesothelioma, Malignant

NCT03546426 2024-10-01

MESOVAX

18 enrolled

Mesothelioma, Malignant, Disease Progression

NCT02707666 2024-07-31

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

Phase 1 Terminated

7 enrolled

BreastGastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant

NCT06281860 2024-02-28

PITHAC

Phase 1 Unknown

39 enrolled

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms

NCT02555007 2022-11-17

NVB Metro

30 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT00652574 2022-10-31

Dasatinib in Resectable Malignant Pleural Mesothelioma

56 enrolled

GenitourinaryOther solid neoplasmThoracic

Mesothelioma, Malignant

NCT04173338 2022-06-14

Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma

Phase 1 Terminated

9 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell

NCT01503177 2021-01-11

Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

15 enrolled

Mesothelioma, Malignant

NCT04201145 2020-11-17

Pembrolizumab + Defactinib In Pleural Mesothelioma

Phase 1 Withdrawn

Mesothelioma, Malignant

NCT00066404 2020-05-13

Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions

BreastDermatologicGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymoma, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Pleural Effusion, Malignant, Endometrial Neoplasms, Breast Neoplasms, Male, Gestational Trophoblastic Disease, Small Cell Lung Carcinoma

NCT00299962 2020-03-18

Gene Therapy for Pleural Malignancies

17 enrolled

Mesothelioma, Malignant, Pleural Effusion

NCT02661659 2018-05-14

A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy

Phase 1 Withdrawn

Mesothelioma, Malignant, Mesothelioma

NCT01355965 2017-09-19

Autologous Redirected RNA Meso-CIR T Cells

18 enrolled

Mesothelioma, Malignant, Disease Progression

NCT01134146 2017-07-21

Radical Pleurectomy/Decortication (PD) and Intensity Modulated Radiotherapy (IMRT)

11 enrolled

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma

NCT02369198 2017-04-07

MesomiR 1: A Phase I Study of TargomiRs as 2nd or 3rd Line Treatment for Patients With Recurrent MPM and NSCLC

27 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT00571298 2017-01-23

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

141 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT02639767 2016-12-07

Concurrent Pemetrexed/Cisplatin With Pleural Intensity Modulated Radiation Therapy for Patients With Unresectable Malignant Pleural Mesothelioma

Phase 1 Withdrawn

Mesothelioma, Malignant

NCT00398138 2016-03-02

Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma

MyeloidOther hematologic neoplasmOther solid neoplasmThoracic

22 enrolled 7 charts

Congenital Abnormalities, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Leukemia, Lung Neoplasms, Myelodysplastic Syndromes

NCT00402766 2015-11-18

Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesothelioma

19 enrolled

BreastGastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT02580747 2015-10-20

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso

Phase 1 Unknown

20 enrolled

Mesothelioma, Malignant, Ovarian Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT01212367 2015-09-22

IFN-alpha

13 enrolled

Mesothelioma, Malignant, Neoplasms

NCT00165555 2014-03-27

Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma

70 enrolled

Mesothelioma, Malignant

NCT01241682 2014-02-27

PMR-MM-002

Mesothelioma, Malignant, Mesothelioma

NCT00003263 2013-04-17

Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

6 enrolled

Mesothelioma, Malignant

NCT00003046 2012-07-30

Interleukin-12 in Treating Patients With Cancer in the Abdomen

GastrointestinalOther solid neoplasmThoracic

29 enrolled

Mesothelioma, Malignant, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Colonic Neoplasms, Gallbladder Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT00003974 2011-03-07

Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage IIIA Non-small Cell Lung Cancer or With Stage I or Stage II Mesothelioma

20 enrolled

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00280982 2010-11-16

Dendritic Cell-based Immunotherapy in Mesothelioma