Clinical Trials Browser

Terminated × Interventional × Mesothelioma, Malignant × Clear all

NCT04158141 2026-05-19

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Phase 3 Terminated

16 enrolled 18 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT03684486 2026-05-06

RehabKBP

Phase NA Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Bronchogenic

NCT03420963 2026-03-20

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Terminated

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT04914897 2025-10-02

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Phase 2 Terminated

106 enrolled 21 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT02863055 2025-09-19

NEMO

Phase 2 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT06299163 2025-07-23

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

Phase 1 Terminated

BreastDermatologicGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

Adenocarcinoma of Lung, Mesothelioma, Malignant, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Leiomyosarcoma, Liposarcoma, Melanoma, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Phase 1/2 Terminated

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05563272 2025-07-10

STARBURST

Phase 2 Terminated

CNSGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Nasopharyngeal Carcinoma, Mesothelioma, Malignant, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma

NCT04213794 2025-02-20

TOASTIT

Phase EARLY_PHASE1 Terminated

GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

NCT05500508 2024-12-24

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Phase 1/2 Terminated

BreastCNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckOther solid neoplasmThoracic

Thyroid Cancer, Papillary, Diffuse Intrinsic Pontine Glioma, Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioma, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05228015 2024-11-18

Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects with Advanced Solid Tumors

Phase 1 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant, Hemangioendothelioma, Epithelioid

NCT02707666 2024-07-31

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

Phase 1 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT03502746 2024-05-14

Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated Mesothelioma

Phase 2 Terminated

34 enrolled 11 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02004028 2024-02-20

Window of Opportunity Study of VS-6063 (Defactinib) in Surgical Resectable Malignant Pleural Mesothelioma Participants

Phase 2 Terminated

35 enrolled 15 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Adenoma, Mesothelioma, Neoplasms, Mesothelial

NCT03393858 2024-02-07

Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma

Phase 1/2 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant, Neoplasms

NCT03233724 2023-05-31

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Phase 1/2 Terminated

9 enrolled 14 charts

GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms

NCT04042480 2023-03-23

A Study of SGN-CD228A in Advanced Solid Tumors

Phase 1 Terminated

DermatologicGastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Melanoma, Colorectal Neoplasms

NCT04173338 2022-06-14

Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma

Phase 1 Terminated

GenitourinaryOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell

NCT02408016 2021-09-13

Genetically Modified T Cells in Treating Patients With Stage III-IV Non-small Cell Lung Cancer or Mesothelioma

Phase 1/2 Terminated

11 enrolled 9 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT00003508 2021-04-27

Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma

Phase 2 Terminated

8 enrolled 5 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT00859495 2020-08-25

Trimodal Lung-Sparing Treatment of Pleural Mesothelioma

Phase 2 Terminated

9 enrolled 4 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02672033 2020-07-24

Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma

Phase NA Terminated

2 enrolled 7 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02357147 2020-03-17

ARTEMIS

Phase 2 Terminated

124 enrolled 10 charts

Other solid neoplasmThoracic

Severe combined immunodeficiency with sensitivity to ionizing radiation, Mesothelioma, Malignant

NCT01143545 2020-03-03

Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas

Phase 1 Terminated

GastrointestinalOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Esophageal Neoplasms, Lung Neoplasms, Sarcoma, Thymoma

NCT00094978 2019-12-12

Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum

Phase 1 Terminated

GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Mesothelioma, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT03175172 2019-04-04

Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM)

Phase 2 Terminated

10 enrolled 11 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT01445392 2018-08-03

SS1(dsFV)PE38 Plus Pemetrexed and Cisplatin to Treat Malignant Pleural Mesothelioma

Phase 1 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT00895648 2017-05-04

Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesothelioma

Phase 2 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT01870609 2017-01-30

COMMAND

Phase 2 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT02372227 2017-01-30

A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma

Phase 1 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT01861301 2016-10-24

Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma

Phase 2 Terminated

18 enrolled 7 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT00165503 2016-09-09

Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate

Phase 2 Terminated

16 enrolled 7 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT00027508 2015-02-24

Ecteinascidin 743 in Treating Patients With Malignant Mesothelioma

Phase 2 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT00028782 2013-01-16

EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer

Phase NA Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT00281125 2012-03-19

Phase I/II Trial of PTK787 and Pemetrexed With or Without Cisplatin for Lung Cancer

Phase 1/2 Terminated

Other solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung