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Phase

Phase 1 1

Status

Active not recruiting 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Myeloid 1Lymphoid 1Dermatologic 1

Conditions

Primary Myelofibrosis 24Leukemia, Myeloid, Acute 16Myeloproliferative Disorders 15Polycythemia Vera 12Leukemia 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Myelodysplastic Syndromes 9Thrombocythemia, Essential 8Graft vs Host Disease 8Recurrence 6Neoplasms 6Myelodysplastic-Myeloproliferative Diseases 4Lymphoma, T-Cell 4Lymphoma, Non-Hodgkin 4Lymphoma 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Breast Neoplasms 4Prostatic Neoplasms 3Pancreatic Neoplasms 3Lymphoma, T-Cell, Cutaneous 3Leukemia, Prolymphocytic, T-Cell 3Leukemia, Myelomonocytic, Chronic 3Hematologic Neoplasms 3Glioblastoma 3Colorectal Neoplasms 3Carcinoma, Non-Small-Cell Lung 3Bronchiolitis Obliterans Syndrome 3Triple Negative Breast Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Multiple Myeloma 2

Interventions

pembrolizumab 12Pemetrexed 9Cisplatin 9Nivolumab 8Carboplatin 8Ipilimumab 7Cyclophosphamide 6fludarabine 5durvalumab 4tremelimumab 2Radiotherapy, Intensity-Modulated 2Gemcitabine 2Cerebral Decortication 2tocilizumab 1tislelizumab 1tazemetostat 1sotorasib 1ruxolitinib 1osimertinib 1olaparib 1obinutuzumab 1naptumomab estafenatox 1fludarabine phosphate 1decitabine and cedazuridine drug combination 1bintrafusp alfa protein, human 1avelumab 1atezolizumab 1Tumor Burden 1Temozolomide 1Tablets 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Mesothelioma × ruxolitinib × 1 year × Clear all
NCT04328844 2026-03-30

A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

iOnctura

Phase 1 Active not recruiting
210 enrolled
DermatologicLymphoidMyeloidOther solid neoplasmThoracic

Uveal Melanoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mesothelioma, Primary Myelofibrosis

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