Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 2 1

Status

Terminated 3Completed 1

Sponsor Class

NIH 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4Other solid neoplasm 4

Conditions

Mesothelioma 4Pleural Effusion, Malignant 1Pancreatic Neoplasms 1Neoplasms 1Myeloproliferative Disorder, Chronic, with Eosinophilia 1Mesothelioma, Malignant 1Lung Neoplasms 1Cholangiocarcinoma 1Carcinoma, Non-Small-Cell Lung 1Carcinoma 1Adenocarcinoma of Lung 1Adenocarcinoma 1

Interventions

LMB-100 4Cyclophosphamide 3fludarabine 2Plicamycin 2Cisplatin 2talazoparib 1pembrolizumab 1olaparib 1fludarabine phosphate 1decitabine and cedazuridine drug combination 1amatuximab 1alvocidib 1aldesleukin 1Surgical Procedures, Operative 1Pentostatin 1Pemetrexed 1Paclitaxel 1Magnetic Resonance Imaging 1Ipilimumab 1Fluorouracil 1Fluorodeoxyglucose F18 1Famotidine 1FANG vaccine 1Electrocardiography 1Echocardiography 1Diphenhydramine 1Dexamethasone 1Depsipeptides 1Cytoreduction Surgical Procedures 1Celecoxib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
NIH × Mesothelioma × LMB-100 × Clear all
NCT04840615 2024-02-02

Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
2 enrolled 14 charts
Other solid neoplasmThoracic

Mesothelioma

NCT02798536 2022-08-23

Mesothelin-Targeted Immunotoxin LMB-100 in People With Malignant Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
21 enrolled 19 charts
Other solid neoplasmThoracic

Mesothelioma

NCT03644550 2021-12-02

Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 2 Terminated
18 enrolled 15 charts
Other solid neoplasmThoracic

Mesothelioma

NCT03436732 2019-11-22

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
5 enrolled 12 charts
Other solid neoplasmThoracic

Mesothelioma

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