Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Terminated 3Completed 1

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

Thoracic 3Other solid neoplasm 3

Conditions

Mesothelioma 3Neoplasms 1Lung Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Adenocarcinoma of Lung 1

Interventions

Pemetrexed 8pembrolizumab 6Cisplatin 6LMB-100 3Carboplatin 3Radiosurgery 2Plicamycin 2Dexamethasone 2Cryotherapy 2vandetanib 1tremelimumab 1tocilizumab 1rebastinib 1pevonedistat 1perflutren 1nintedanib 1iodixanol 1fludarabine phosphate 1fludarabine 1epacadostat 1enzalutamide 1durvalumab 1defactinib 1anetumab ravtansine 1amatuximab 1alvocidib 1aldesleukin 1Vinorelbine 1Sulfur Hexafluoride 1Radiotherapy, Intensity-Modulated 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Terminated × Mesothelioma × LMB-100 × Clear all
NCT04840615 2024-02-02

Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
2 enrolled 14 charts
Other solid neoplasmThoracic

Mesothelioma

NCT03644550 2021-12-02

Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 2 Terminated
18 enrolled 15 charts
Other solid neoplasmThoracic

Mesothelioma

NCT03436732 2019-11-22

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
5 enrolled 12 charts
Other solid neoplasmThoracic

Mesothelioma

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