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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1

Conditions

Prostatic Neoplasms 29Breast Neoplasms 28Brain Neoplasms 21Neoplasms 16Glioma 10Pancreatic Neoplasms 9Head and Neck Neoplasms 8Lymphoma 7Uterine Cervical Neoplasms 6Urinary Bladder Neoplasms 6Rectal Neoplasms 6Glioblastoma 6Colonic Neoplasms 6Carcinoma, Hepatocellular 6Lymphoma, Non-Hodgkin 5Lung Neoplasms 5Astrocytoma 5Triple Negative Breast Neoplasms 4Squamous Cell Carcinoma of Head and Neck 4Liver Neoplasms 4Disease 4Central Nervous System Neoplasms 4Stomach Neoplasms 3Spinal Cord Neoplasms 3Sarcoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Esophageal Neoplasms 3Carcinoma in Situ 3Retinoblastoma 2Pathologic Complete Response 2

Interventions

Pemetrexed 40Cisplatin 35pembrolizumab 21Nivolumab 17Carboplatin 16Ipilimumab 13Gemcitabine 10Cyclophosphamide 9fludarabine 6durvalumab 6Bevacizumab 6Radiotherapy, Intensity-Modulated 4LMB-100 4Drug Therapy 4Dexamethasone 4tremelimumab 3tazemetostat 3spartalizumab 3olaparib 3niraparib 3atezolizumab 3anetumab ravtansine 3amatuximab 3Vinorelbine 3Paclitaxel 3Oxaliplatin 3Imatinib Mesylate 3Fluorouracil 3Cerebral Decortication 3Blood Specimen Collection 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Mesothelioma × Magnetic Resonance Imaging × Clear all
NCT04840615 2024-02-02

Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
2 enrolled 14 charts
Other solid neoplasmThoracic

Mesothelioma

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