Clinical Trials

33 enrolled

Phase 2 Not yet recruiting

Mesothelioma, Malignant, Mesothelioma

NCT07602946 2026-05-22

SELECTmeso

Mesothelioma

NCT04158141 2026-05-19

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Phase 3 Terminated

16 enrolled 18 charts

Phase 2 Active not recruiting

Mesothelioma, Malignant, Mesothelioma

NCT00715611 2026-05-14

Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma

65 enrolled

Mesothelioma

NCT03683680 2026-05-05

Prospectively Collected Pleural Biopsies for Validation of Malignant Pleural Mesothelioma Prognostic Biomarkers

240 enrolled

Mesothelioma

NCT06638931 2026-04-15

ANTARES

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther solid neoplasmSarcomaThoracic

28 enrolled

Urachal adenocarcinoma, Urachal cancer, Fibrolamellar hepatocellular carcinoma, Secretory breast carcinoma, Carcinoma, Ovarian Epithelial, Adrenal Gland Neoplasms, Anus Neoplasms, Biliary Tract Neoplasms, Carcinosarcoma, Carcinoma, Adenoid Cystic, Fallopian Tube Neoplasms, Fibrosarcoma, Gallbladder Neoplasms, Granulosa Cell Tumor, Hemangiosarcoma, Leiomyosarcoma, Mesothelioma, Neuroblastoma, Parathyroid Neoplasms, Penile Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Thyroid Neoplasms, Trophoblastic Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Hepatoblastoma, Endodermal Sinus Tumor, Neuroectodermal Tumors, Primitive, Cholangiocarcinoma, Sertoli-Leydig Cell Tumor, Neurofibrosarcoma, Hemangioblastoma, Neuroendocrine Tumors

NCT07514793 2026-04-07

Iparomlimab Plus Tovorilimab Combined With Bevacizumab and Chemotherapy as First-Line Treatment for Advanced Mesothelioma

Phase 2 Not yet recruiting

37 enrolled

Phase NA Active not recruiting

Mesothelioma

NCT04450043 2026-03-27

The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance

21 enrolled

Phase NA Active not recruiting

Carcinoma, Non-Small-Cell Lung, Mesothelioma, Small Cell Lung Carcinoma

NCT04028570 2026-03-05

SMARTER

15 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Mesothelioma

NCT07420010 2026-02-19

An Open-label, Single-arm Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of KT032 Cell Injection in Patients With Mesothelin-positive Advanced Solid Tumors.

24 enrolled

GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Mesothelioma, Ovarian Neoplasms

NCT07126509 2026-02-17

Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

Mesothelioma, Malignant, Mesothelioma

NCT02662504 2026-02-05

MesoPDT

6 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT04166734 2026-02-04

MESO-PRIME

Phase 1 Terminated

5 enrolled 13 charts

Mesothelioma

NCT04334759 2026-01-22

DREAM3R

Phase 3 Completed

214 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT03075527 2026-01-08

A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural Mesothelioma

Phase 2 Terminated

19 enrolled 12 charts

Mesothelioma

NCT05005429 2025-12-23

BIMES

47 enrolled 9 charts

Mesothelioma, Malignant, Mesothelioma

NCT02611037 2025-12-18

Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma

34 enrolled 12 charts

Mesothelioma, Malignant, Mesothelioma

NCT05730816 2025-11-21

MAGIC-AKI

130 enrolled

Mesothelioma

NCT04115254 2025-11-13

Stereotactic Magnetic Resonance Guided Radiation Therapy

CNSGastrointestinalGenitourinaryOther solid neoplasmThoracic

397 enrolled

Brain Neoplasms, Kidney Neoplasms, Lung Neoplasms, Mesothelioma, Pancreatic Neoplasms, Prostatic Neoplasms

NCT06538376 2025-10-29

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

230 enrolled

Phase 1/2 Active not recruiting

Airway Obstruction, Pulmonary Atelectasis, Hemothorax, Mesothelioma, Pleural Effusion, Pneumonia, Pneumothorax, Pulmonary Edema, Pulmonary Embolism, Respiratory Paralysis, Rib Fractures

NCT02414269 2025-10-08

Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin

113 enrolled

BreastOther solid neoplasmThoracic

Breast Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis

NCT05932199 2025-09-25

Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma

Phase 1/2 Recruiting

52 enrolled

Phase 1/2 Not yet recruiting

Mesothelioma

NCT07131345 2025-08-20

Study of Iparomlimab and Tuvonralimab Plus Chemotherapy in Malignant Mesothelioma

55 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT06057935 2025-07-22

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

64 enrolled

Other solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Mesothelioma

NCT00629343 2025-06-05

Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide

Phase 1 Completed

27 enrolled 7 charts

Mesothelioma, Sarcoma

NCT05455424 2025-05-15

NERO

88 enrolled

GenitourinaryOther solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma, Recurrence

NCT04040231 2025-05-13

Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma

Phase 1 Completed

10 enrolled

Mesothelioma, Malignant, Mesothelioma, Wilms Tumor

NCT04515836 2025-05-06

Olaparib in Patients With HRD Malignant Mesothelioma

56 enrolled

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma

NCT06946498 2025-04-27

FLAT

100 enrolled

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Pleural Effusion, Pleural Effusion, Malignant

NCT03063450 2025-04-10

CONFIRM

Phase 3 Completed

332 enrolled

Phase 2 Active not recruiting

Mesothelioma

NCT04802876 2025-03-21

ACROPOLI

184 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Adenocarcinoma Of Esophagus, Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Uveal Melanoma, Anus Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasms, Unknown Primary, Sarcoma, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03560973 2025-03-13

RAMES

164 enrolled

Mesothelioma

NCT04996017 2025-03-13

AtezoMeso

Phase 3 Recruiting

162 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT03656549 2024-12-17

IMPROVE-I

Phase 4 Completed

6 enrolled

Phase NA Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Mesothelioma

NCT06310993 2024-12-03

BICEP

GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Pancreatic Neoplasms

NCT02748798 2024-10-15

Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders

Phase EARLY_PHASE1 Terminated

10 enrolled

Asbestosis, Asthma, Bronchiectasis, Cystic Fibrosis, Emphysema, Rhinitis, Allergic, Seasonal, Hypertension, Pulmonary, Lung Neoplasms, Mesothelioma, Pulmonary Embolism, Pulmonary Fibrosis, Lung Diseases, Interstitial, Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive

NCT05660616 2024-08-27

Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural Mesothelioma

40 enrolled

DermatologicGastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Mesothelioma

NCT02714374 2024-08-06

GL-ONC1 Administered Intravenously Prior to Surgery to Patients With Solid Organ Cancers

Phase 1 Terminated

5 enrolled

Gallbladder Neoplasms, Melanoma, Mesothelioma, Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03867578 2024-07-31

Magnetic Resonance Imaging for Detection of Peritoneal Mesothelioma

Phase NA Completed

26 enrolled

Mesothelioma

NCT06491784 2024-07-09

EXTRA-Meso (EXercise TheRApy in Mesothelioma) Feasibility

40 enrolled

Mesothelioma

NCT06196294 2024-06-26

GPC3/Mesothelin-CAR-γδT Cells Against Cancers

Phase 1 Recruiting

GastrointestinalOther solid neoplasmThoracic

Liver Neoplasms, Lung Neoplasms, Mesothelioma, Pancreatic Neoplasms

NCT03319537 2024-05-23

Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma

Phase 1/2 Terminated

9 enrolled 9 charts

Phase 2 Active not recruiting

Mesothelioma

NCT04300244 2024-02-29

NIPU

118 enrolled

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Neoplasms

NCT05041062 2024-01-03

A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesothelioma

2 enrolled 8 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Lung Neoplasms, Mesothelioma

NCT04670445 2023-10-23

UPLIFT

Phase NA Unknown

210 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Melanoma, Mesothelioma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms

NCT01401907 2023-10-19

Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies

Phase NA Completed

351 enrolled 15 charts

GastrointestinalOther solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Liver Neoplasms, Mesothelioma, Pancreatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma

NCT03207347 2023-09-15

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

37 enrolled 15 charts

Uveal Melanoma, Carcinoma, Renal Cell, Mesothelioma, Cholangiocarcinoma

NCT05404022 2023-09-13

CanBenefitII

Phase NA Completed

11 enrolled