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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gastrointestinal 1

Conditions

Carcinoma, Non-Small-Cell Lung 8Advanced Solid Tumor 7Squamous Cell Carcinoma of Head and Neck 5Neoplasm Metastasis 5Colorectal Neoplasms 5Stomach Neoplasms 4Melanoma 4Carcinoma, Hepatocellular 4Solid Tumor 3Solid Tumors 2Lymphoma 2Head and Neck Neoplasms 2Esophageal Squamous Cell Carcinoma 2Carcinoma, Renal Cell 2Advanced Solid Tumors 2Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Testicular Germ Cell Tumor 1Skin Neoplasms 1Simpson-Golabi-Behmel syndrome 1Sarcoma 1Recurrence 1Rectal Neoplasms 1Pancreatic Neoplasms 1Pancreatic Ductal Adenocarcinoma 1Neuroendocrine Tumors 1Neoplasms 1Nasopharyngeal Carcinoma 1Muscle Invasive Bladder Cancer 1

Interventions

tislelizumab 1bintrafusp alfa protein, human 1avelumab 1Tomography, X-Ray Computed 1Nivolumab 1Ipilimumab 1Injections 1Infusions, Intravenous 1Gemcitabine 1Electrocardiography 1Echocardiography 1DOXO-EMCH 1Cetuximab 1(2,4-dihydroxy-5-isopropylphenyl)-(5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl)methanone 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Metastatic Solid Tumors × tislelizumab × Clear all
NCT06585488 2026-06-03

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

BeOne Medicines

Phase 1 Terminated
47 enrolled
GastrointestinalOther solid neoplasmThoracic

Metastatic Solid Tumors

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