Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 35Leukemia 30Precursor Cell Lymphoblastic Leukemia-Lymphoma 27Lymphoma 27Lymphoma, Non-Hodgkin 22Burkitt Lymphoma 21Lymphoma, Mantle-Cell 20Leukemia, Lymphocytic, Chronic, B-Cell 20Lymphoma, Large B-Cell, Diffuse 19Lymphoma, Follicular 19Neuroblastoma 18Myelodysplastic Syndromes 18Multiple Myeloma 18Lymphoma, Large-Cell, Immunoblastic 17Lymphoma, B-Cell, Marginal Zone 17Hodgkin Disease 15Astrocytoma 14Medulloblastoma 13Breast Neoplasms 13Recurrence 12Central Nervous System Neoplasms 12Sarcoma 11Myeloproliferative Disorders 10Leukemia, Myeloid, Chronic-Phase 10Ovarian Neoplasms 9Leukemia, Myeloid, Accelerated Phase 9Familial ependymoma 9Carcinoma, Ovarian Epithelial 9Blast Crisis 9Optic Nerve Glioma 8

Interventions

Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Filgrastim 2trametinib 1sonidegib 1ribociclib 1prexasertib 1pegfilgrastim 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Microphthalmia, Isolated, with Coloboma 5 × Filgrastim × Clear all
NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
21 enrolled
CNS

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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