Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Lymphoma 155Leukemia 127Precursor Cell Lymphoblastic Leukemia-Lymphoma 92Lymphoma, Non-Hodgkin 81Leukemia, Myeloid, Acute 80Lymphoma, Large B-Cell, Diffuse 75Multiple Myeloma 71Lymphoma, Follicular 64Hodgkin Disease 64Breast Neoplasms 64Leukemia, Lymphocytic, Chronic, B-Cell 63Lymphoma, Mantle-Cell 62Burkitt Lymphoma 60Myelodysplastic Syndromes 55Lymphoma, Large-Cell, Immunoblastic 53Sarcoma 41Lymphoma, B-Cell, Marginal Zone 40Neuroblastoma 37Central Nervous System Neoplasms 34Neoplasms, Plasma Cell 32Leukemia, Myeloid, Chronic-Phase 32Ovarian Neoplasms 31Leukemia, Myeloid, Accelerated Phase 30Myeloproliferative Disorders 28Dendritic Cell Sarcoma, Interdigitating 28Recurrence 27Congenital Abnormalities 27Blast Crisis 26Neutropenia 24Anemia, Refractory, with Excess of Blasts 22

Interventions

Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Filgrastim 2trametinib 1sonidegib 1ribociclib 1prexasertib 1pegfilgrastim 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Microphthalmia, Isolated, with Coloboma 5 × Filgrastim × Clear all
NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
21 enrolled
CNS

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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