Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Pancreatic Neoplasms 170Neoplasms 66Carcinoma, Non-Small-Cell Lung 49Neoplasm Metastasis 37Unspecified Adult Solid Tumor, Protocol Specific 25Ovarian Neoplasms 21Breast Neoplasms 21Urinary Bladder Neoplasms 20Cholangiocarcinoma 20Lymphoma 19Colorectal Neoplasms 18Lymphoma, Non-Hodgkin 17Lung Neoplasms 17Sarcoma 16Hodgkin Disease 14Fallopian Tube Neoplasms 14Biliary Tract Neoplasms 13Lymphoma, Large B-Cell, Diffuse 12Gallbladder Neoplasms 11Colonic Neoplasms 11Carcinoma, Ovarian Epithelial 11Stomach Neoplasms 10Recurrence 10Solid Tumors 9Bile Duct Neoplasms 8Adenocarcinoma 8Triple Negative Breast Neoplasms 7Small Cell Lung Carcinoma 7Rectal Neoplasms 7Melanoma 7

Interventions

Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Filgrastim 2trametinib 1sonidegib 1ribociclib 1prexasertib 1pegfilgrastim 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Microphthalmia, Isolated, with Coloboma 5 × Gemcitabine × Clear all
NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
21 enrolled
CNS

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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