Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 104Multiple Myeloma 66Lymphoma 60Precursor Cell Lymphoblastic Leukemia-Lymphoma 57Myelodysplastic Syndromes 51Lymphoma, Non-Hodgkin 51Leukemia 50Hodgkin Disease 42Lymphoma, Mantle-Cell 29Lymphoma, Large B-Cell, Diffuse 29Leukemia, Lymphocytic, Chronic, B-Cell 26Leukemia, Myelogenous, Chronic, BCR-ABL Positive 23Lymphoma, Follicular 22Burkitt Lymphoma 22Breast Neoplasms 22Recurrence 20Neoplasms, Plasma Cell 18Neuroblastoma 17Hematologic Neoplasms 17Lymphoma, B-Cell, Marginal Zone 15Myeloproliferative Disorders 14Lymphoma, Large-Cell, Immunoblastic 14Leukemia, Myelomonocytic, Chronic 12Leukemia, Biphenotypic, Acute 12Congenital Abnormalities 12Blast Crisis 10Anemia, Refractory, with Excess of Blasts 10Retinoblastoma 9Central Nervous System Neoplasms 9Sarcoma 8

Interventions

Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Filgrastim 2trametinib 1sonidegib 1ribociclib 1prexasertib 1pegfilgrastim 1Temozolomide 1HhAntag691 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Microphthalmia, Isolated, with Coloboma 5 × Granulocyte Colony-Stimulating Factor × Clear all
NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
21 enrolled
CNS

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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