Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Multiple Myeloma 60Lymphoma 56Leukemia, Myeloid, Acute 51Leukemia 50Lymphoma, Non-Hodgkin 48Precursor Cell Lymphoblastic Leukemia-Lymphoma 46Hodgkin Disease 36Myelodysplastic Syndromes 28Lymphoma, Large B-Cell, Diffuse 27Breast Neoplasms 24Lymphoma, Mantle-Cell 23Neuroblastoma 22Leukemia, Lymphocytic, Chronic, B-Cell 22Burkitt Lymphoma 17Lymphoma, Follicular 16Leukemia, Myelogenous, Chronic, BCR-ABL Positive 16Central Nervous System Neoplasms 13Lymphoma, Large-Cell, Immunoblastic 12Sarcoma 11Neoplasms, Plasma Cell 11Brain Neoplasms 11Recurrence 10Lymphoma, B-Cell, Marginal Zone 10Neoplasms 9Hematologic Neoplasms 9Congenital Abnormalities 9Myeloproliferative Disorders 8Leukemia, Myelomonocytic, Chronic 8Leukemia, Biphenotypic, Acute 8Graft vs Host Disease 8

Interventions

Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Filgrastim 2trametinib 1sonidegib 1ribociclib 1prexasertib 1pegfilgrastim 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Microphthalmia, Isolated, with Coloboma 5 × Granulocyte Colony-Stimulating Factor × Clear all
NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
21 enrolled
CNS

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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