Clinical Trials Browser

Phase 3 × Mouth Neoplasms × Clear all

NCT06589804 2026-05-22

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Phase 3 Recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms

NCT05721755 2026-05-05

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Phase 3 Active not recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT07441681 2026-05-04

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

Phase 3 Not yet recruiting

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT06798922 2026-03-03

OPTIFLAP

Phase 3 Recruiting

Mouth Neoplasms

NCT07402538 2026-02-11

Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell Carcinoma

Phase 3 Not yet recruiting

Mouth Neoplasms, Oropharyngeal Neoplasms

NCT06737822 2025-03-04

SurVIC

Phase 3 Recruiting

Head and Neck Neoplasms, Mouth Neoplasms

NCT05369234 2024-10-10

Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

Phase 3 Completed

GastrointestinalHead & Neck

Esophageal Neoplasms, Laryngeal Neoplasms, Mediastinal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00964977 2022-02-25

Effectiveness of Adjuvant Radiotherapy in Small Oropharyngeal Squamous Cell Cancer and Single Lymph Node Metastasis.

Phase 3 Completed

Head and Neck Neoplasms, Lymphatic Metastasis, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00402779 2020-04-21

Erlotinib Prevention of Oral Cancer (EPOC)

Phase 3 Completed

303 enrolled 11 charts

Carcinoma in Situ, Mouth Neoplasms

NCT00158678 2020-04-15

IMRT Plus Cisplatin Versus Conventional Radiotherapy Plus Cisplatin in Stage III-IV HNSCC

Phase 3 Completed

Hypopharyngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT03824925 2019-01-31

Efficacy of Zinc on Concurrent Chemo-radiotherapy Induced Taste Alterations

Phase 3 Completed

Dysgeusia, Mouth Neoplasms

NCT03685409 2018-09-26

Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

Phase 3 Unknown

Mouth Neoplasms

NCT00359645 2017-05-16

Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population

Phase 3 Completed

GastrointestinalHead & Neck

Esophageal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms

NCT00537199 2016-05-13

OraTest in Combination With Visual Examination and Visual Examination Alone

Phase 3 Terminated

1 enrolled 2 charts

Head and Neck Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00022373 2014-10-15

Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer

Phase 3 Unknown

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries, Salivary Gland Neoplasms

NCT01039298 2014-09-10

Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL

Phase 3 Unknown

Margins of Excision, Mouth Neoplasms, Recurrence

NCT00008398 2013-11-19

Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Phase 3 Completed

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries

NCT00158652 2011-11-08

Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT00655421 2009-07-03

Oral Cancer Screening in Mumbai, India by Primary Health Care Workers

Phase 3 Unknown

Head & NeckOther neoplasm

Mouth Neoplasms, Precancerous Conditions, Tobacco Use

NCT00750503 2008-09-10

Workplace Tobacco Cessation And Oral Cancer Screening Study

Phase 3 Completed

Mouth Neoplasms, Tobacco Use Cessation

NCT00193843 2005-12-26

Oral Cancer Adjuvant Therapy (OCAT) Trial

Phase 3 Unknown

Mouth Neoplasms