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Phase

Phase 1 2Phase 1/2 1

Status

Completed 2Active not recruiting 1

Sponsor Class

INDUSTRY 2OTHER 1

Study Type

Interventional 3

Sponsor

Cancer Type

Lymphoid 3Dermatologic 3

Conditions

Lymphoma, T-Cell, Peripheral 16Lymphoma, T-Cell 10Recurrence 7Lymphoma 6Lymphoma, Non-Hodgkin 5Lymphoma, Large-Cell, Anaplastic 5Immunoblastic Lymphadenopathy 4Mycosis Fungoides 3Lymphoma, T-Cell, Cutaneous 3Lymphoma, Follicular 3Hodgkin Disease 3Carcinoma, Non-Small-Cell Lung 3Waldenstrom Macroglobulinemia 2Unspecified Adult Solid Tumor, Protocol Specific 2Sezary Syndrome 2Neoplasm Metastasis 2Multiple Myeloma 2Lymphoma, Mantle-Cell 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, B-Cell 2Lung Neoplasms 2Esophageal Squamous Cell Carcinoma 2Burkitt Lymphoma 2Adenocarcinoma Of Esophagus 2Urinary Bladder Neoplasms 1Subcutaneous panniculitis-like T-cell lymphoma 1Stomach Neoplasms 1Smoking 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1

Interventions

Peripheral Blood Stem Cell Transplantation 39fludarabine phosphate 37Cyclophosphamide 33Mycophenolic Acid 28Whole-Body Irradiation 24Cyclosporine 24Tacrolimus 22Radiotherapy 19Methotrexate 18Busulfan 18Antilymphocyte Serum 17Flow Cytometry 14Filgrastim 14Etoposide 14Vorinostat 11Bortezomib 11Bexarotene 11mogamulizumab 10Methylprednisolone 10Lenalidomide 10pembrolizumab 9Rituximab 9Melphalan 9Gemcitabine 9Brentuximab Vedotin 9romidepsin 8Therapeutics 8Psychiatric Rehabilitation 8Polymerase Chain Reaction 8Methoxsalen 8

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Mycosis Fungoides × 10-propargyl-10-deazaaminopterin × Clear all
NCT03598998 2026-05-26

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

City of Hope Medical Center

Phase 1/2 Active not recruiting
13 enrolled 12 charts
DermatologicLymphoid

Subcutaneous panniculitis-like T-cell lymphoma, Immunoblastic Lymphadenopathy, Lymphoma, Follicular, Mycosis Fungoides, Lymphoma, T-Cell, Lymphoma, Large-Cell, Anaplastic, Enteropathy-Associated T-Cell Lymphoma

NCT00554827 2020-01-03

Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Acrotech Biopharma Inc.

Phase 1 Completed
55 enrolled
DermatologicLymphoid

Lymphoma, Mycosis Fungoides, Recurrence, Sezary Syndrome, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT01134341 2019-12-18

Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Acrotech Biopharma Inc.

Phase 1 Completed
34 enrolled
DermatologicLymphoid

Mycosis Fungoides, Recurrence, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Lymphoma, Primary Cutaneous Anaplastic Large Cell

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