Clinical Trials

600 enrolled

GATA2 Deficiency, Herpes Simplex, Leukemia, Myelodysplastic Syndromes

NCT05588154 2026-04-13

Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies

1,000 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05350748 2026-03-31

Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS

Classical hematologyMyeloidOther hematologic neoplasm

1,100 enrolled

Cytopenia, Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute

NCT04902833 2026-03-25

Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

Classical hematologyMyeloidOther hematologic neoplasm

100 enrolled

Pyruvate Kinase Deficiency of Red Cells, Anemia, Hemolytic, Congenital, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases

NCT05969821 2026-03-23

CHIS

Not yet recruiting

5,000 enrolled

VEXAS syndrome, Autoimmune Diseases, Hematologic Diseases, Immune System Diseases, Inflammation, Leukemia, Lymphoma, Lymphoproliferative Disorders, Monoclonal Gammopathy of Undetermined Significance, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases

NCT04635384 2026-03-18

ACROBAT

307 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06510868 2026-03-05

MDS & PRRT

45 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT04263181 2026-03-02

AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration

80 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01728402 2026-02-17

Pathogenesis of Hematologic Malignancies

Enrolling by invitation

5,000 enrolled

LymphoidMyeloid

Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloproliferative Disorders

NCT02269592 2026-02-12

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

LymphoidMyeloidOther hematologic neoplasmPlasma cell

10,000 enrolled

Smoldering Multiple Myeloma, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT04645199 2026-02-12

NICHE

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

2,300 enrolled

Anemia, Aplastic, Anemia, Hemolytic, Autoimmune, Hemophilia B, Hemoglobinuria, Paroxysmal, Hemophilia A, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Hemostatic Disorders, Leukemia, Large Granular Lymphocytic

NCT02775383 2026-02-03

MDS

Completed

2,115 enrolled

Classical hematologyMyeloid

Cytopenia, Myelodysplastic Syndromes, Myeloproliferative Disorders

NCT07249476 2025-12-16

ENKLA-M

Not yet recruiting

55 enrolled

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT07019155 2025-12-15

Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants

510 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT04167683 2025-12-08

Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant

144 enrolled

Hematologic Diseases, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04115241 2025-11-10

Activity Levels in Bone Marrow Transplant Patients

MyeloidOther hematologic neoplasmPlasma cell

200 enrolled

Leukemia, Multiple Myeloma, Myelodysplastic Syndromes

NCT03452774 2025-10-28

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidMyeloidNETOther hematologic neoplasmThoracic

50,000 enrolled

Turcot syndrome, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Central Nervous System Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Neuroendocrine Tumors, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Primary Myelofibrosis

NCT01137643 2025-10-27

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Classical hematologyDermatologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

15,000 enrolled

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Anemia, Aplastic, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Polycythemia Vera, Sezary Syndrome, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis, Intraocular Lymphoma

NCT04188678 2025-10-27

REBOUND

Completed

126 enrolled

Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT03016806 2025-10-10

Umbilical Cord Blood Transplantation From Unrelated Donors

Classical hematologyLymphoidMyeloidPlasma cell

30 enrolled

Anemia, Aplastic, Immunologic Deficiency Syndromes, Lymphoma, Metabolic Diseases, Multiple Myeloma, Myelodysplastic Syndromes

NCT07205523 2025-10-03

HALO-SCT

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

1,000 enrolled

Anemia, Aplastic, Hemophilia A, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hemostatic Disorders

NCT04537871 2025-09-25

Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study

LymphoidMyeloidOther hematologic neoplasmPlasma cell

350 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01311258 2025-09-17

MRD

400 enrolled

LymphoidMyeloidPlasma cell

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT07150468 2025-09-02

Establishment of a Strategy for Preventing Graft-versus-host Disease After Allogeneic Hematopoietic Cell Transplantation by Exploring Immune Mechanisms of Regulatory and Effector T Cells

Completed

146 enrolled

Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders

NCT07145411 2025-08-28

HOPE

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

10 enrolled

Anemia, Aplastic, Anemia, Sickle Cell, Lymphoma, Myelodysplastic Syndromes, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05150561 2025-08-11

Muscle Dysfunction in Patients With Haematological Diseases

216 enrolled

Hematologic Diseases, Lymphoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06944119 2025-07-28

Assesment of the Immune Response to RSV Vaccine in Patients With Myeloma, Lymphoma and Hematological Leukemia

LymphoidMyeloidPlasma cell

250 enrolled

Lymphoma, Myelodysplastic Syndromes, Neoplasms, Plasma Cell

NCT06270771 2025-07-08

OURA MDS

60 enrolled

Myeloid

Myelodysplastic Syndromes, Myelodysplastic-Myeloproliferative Diseases

NCT01688011 2025-07-03

Connect® Myeloid Disease Registry

Terminated

2,013 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Primary Myelofibrosis

NCT01137825 2025-06-25

Registry of Older Patients With Cancer

DermatologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

3,000 enrolled

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Sezary Syndrome, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis, Intraocular Lymphoma

NCT04968834 2025-06-12

Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy

300 enrolled

Leukemia, Myelodysplastic Syndromes

NCT06999954 2025-05-31

SDS-GPS

Classical hematologyGastrointestinalLymphoidMyeloid

8,000 enrolled

Neutropenia, severe chronic, Neutropenia, Severe Congenital, Autosomal Recessive 3, Congenital Bone Marrow Failure Syndromes, Shwachman-Diamond Syndrome, Primary Immunodeficiency Diseases, Immunologic Deficiency Syndromes, Lymphoma, Follicular, Myelodysplastic Syndromes, Neoplastic Syndromes, Hereditary, Exocrine Pancreatic Insufficiency, Pancytopenia

NCT06956755 2025-05-06

Registry of Myelodysplastic Syndromes and Therapy-related Acute Myeloid Leukemia

6,990 enrolled