Announcements Trials
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Phase

Phase 2 33Phase 1 27Phase 1/2 13Phase 3 3Phase 2/3 3Phase NA 1Phase EARLY_PHASE1 1Phase 4 1

Status

Completed 2Unknown 1

Sponsor Class

INDUSTRY 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 3Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 19Myelodysplastic Syndromes 3Leukemia, Myelomonocytic, Chronic 3Neoplasms 2Lymphoma, Large B-Cell, Diffuse 2Pathologic Complete Response 1Myeloproliferative Disorders 1Myelodysplastic-Myeloproliferative Diseases 1Lymphoma, T-Cell, Peripheral 1Leukemia, Myelomonocytic, Acute 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Monocytic, Acute 1Leukemia, Megakaryoblastic, Acute 1Leukemia, Erythroblastic, Acute 1Leukemia 1Congenital Abnormalities 1Anemia, Refractory, with Excess of Blasts 1Anemia, Refractory 1

Interventions

Methotrexate 11Busulfan 11Cytarabine 10fludarabine 8Daunorubicin 8Cyclophosphamide 8fludarabine phosphate 7Whole-Body Irradiation 7Etoposide 7Tacrolimus 6Mitoxantrone 5Melphalan 5Idarubicin 5Thioguanine 4Peripheral Blood Stem Cell Transplantation 4Mycophenolic Acid 4Azacitidine 4thymoglobulin 3Radiotherapy 3Filgrastim 3Early Intervention, Educational 3Decitabine 3Cyclosporine 3Asparaginase 3Antilymphocyte Serum 3merphos 2luspatercept 2decitabine and cedazuridine drug combination 2Tretinoin 2Stem Cell Transplantation 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 3 × Myelodysplastic Syndromes × Decitabine × Clear all
NCT03306264 2024-08-27

Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AML

Astex Pharmaceuticals, Inc.

Phase 3 Completed
227 enrolled 37 charts 1 FDA
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT00043381 2024-08-02

Decitabine Versus Supportive Care in Adults With Advanced-stage MDS

Astex Pharmaceuticals, Inc.

Phase 3 Completed
160 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00043134 2010-04-13

Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 3 Unknown
220 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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