Announcements Trials
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Phase

Phase 2 3Phase 1 3Phase 1/2 2

Status

Completed 2Unknown 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Other hematologic neoplasm 3Myeloid 3Classical hematology 3

Conditions

Ovarian Neoplasms 28Small Cell Lung Carcinoma 26Lung Neoplasms 20Neuroblastoma 17Carcinoma, Ovarian Epithelial 17Fallopian Tube Neoplasms 12Brain Neoplasms 10Uterine Cervical Neoplasms 8Sarcoma 8Leukemia 8Leukemia, Myeloid, Acute 6Central Nervous System Neoplasms 6Recurrence 5Medulloblastoma 5Lymphoma 5Gliosarcoma 5Glioblastoma 5Sarcoma, Ewing 4Rhabdoid Tumor 4Retinoblastoma 4Osteosarcoma 4Neuroectodermal Tumors, Primitive, Peripheral 4Neoplasms 4Burkitt Lymphoma 4Wilms Tumor 3Neoplasm Metastasis 3Myelodysplastic Syndromes 3Lymphoma, Non-Hodgkin 3Lymphoma, Large B-Cell, Diffuse 3Glioma 3

Interventions

Cyclophosphamide 116fludarabine phosphate 101Busulfan 83Tacrolimus 75fludarabine 73Mycophenolic Acid 71Whole-Body Irradiation 65Peripheral Blood Stem Cell Transplantation 59Antilymphocyte Serum 58Cyclosporine 53Azacitidine 53Melphalan 50Cytarabine 47Filgrastim 43Methotrexate 41Granulocyte Colony-Stimulating Factor 34Decitabine 33Radiotherapy 28Thiotepa 27Cord Blood Stem Cell Transplantation 27thymoglobulin 26Stem Cell Transplantation 26Clofarabine 22Methylprednisolone 20Sirolimus 19Alemtuzumab 16venetoclax 15Specimen Handling 14sargramostim 13Etoposide 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 2 × Myelodysplastic Syndromes × Topotecan × Clear all
NCT00003675 2016-07-20

Topotecan in Treating Patients With Myelodysplastic Syndrome

Alliance for Clinical Trials in Oncology

Phase 2 Completed
100 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00003827 2013-12-04

Combination Chemotherapy in Treating Patients With Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 2 Unknown
25 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes

NCT00053287 2010-06-10

Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS

Case Comprehensive Cancer Center

Phase 2 Completed
42 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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