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Phase

Phase 2 1Phase 1/2 1

Status

Terminated 2Completed 2Recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2Plasma cell 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 19Lymphoma 19Lymphoma, Large B-Cell, Diffuse 16Leukemia 11Lymphoma, Non-Hodgkin 10Burkitt Lymphoma 10Recurrence 9Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma, Follicular 6Neoplasms 5Lymphoma, B-Cell 5Leukemia, Myeloid, Acute 4Multiple Myeloma 3Medulloblastoma 3Lymphoma, T-Cell, Peripheral 3Hodgkin Disease 3Waldenstrom Macroglobulinemia 2Sezary Syndrome 2Sarcoma, Ewing 2Neuroblastoma 2Neoplasms by Histologic Type 2Myelodysplastic Syndromes 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, T-Cell 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Extranodal NK-T-Cell 2Lymphatic Diseases 2Leukemia, Lymphocytic, Chronic, B-Cell 2Leukemia, Biphenotypic, Acute 2

Interventions

Cyclophosphamide 39fludarabine phosphate 36Azacitidine 32fludarabine 24Whole-Body Irradiation 22Busulfan 22Tacrolimus 21Antilymphocyte Serum 21Mycophenolic Acid 19Filgrastim 17Methotrexate 16Melphalan 15Peripheral Blood Stem Cell Transplantation 13venetoclax 12thymoglobulin 12Granulocyte Colony-Stimulating Factor 12Cytarabine 12Cyclosporine 12Thiotepa 9Cord Blood Stem Cell Transplantation 9Alemtuzumab 8Rituximab 7Radiotherapy 7Methylprednisolone 7Decitabine 7Clofarabine 7Lenalidomide 6Stem Cell Transplantation 5Sirolimus 5Nivolumab 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Terminated × Myelodysplastic Syndromes × Vincristine × Clear all
NCT04752163 2025-05-23

DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Terminated
17 enrolled 15 charts
LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00074490 2018-12-31

Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

National Institutes of Health Clinical Center (CC)

Phase 2 Terminated
442 enrolled 17 charts
LymphoidMyeloidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders

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