Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

INDUSTRY 5OTHER 2NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2

Conditions

Leukemia, Myeloid, Acute 3Myelodysplastic Syndromes 2Multiple Myeloma 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma 1Lung Neoplasms 1Dendritic Cell Sarcoma, Interdigitating 1Cholangiocarcinoma 1Carcinoma, Hepatocellular 1Acromesomelic dysplasia, Maroteaux type 1

Interventions

Cytarabine 18fludarabine phosphate 17Cyclophosphamide 12Busulfan 11Filgrastim 10Peripheral Blood Stem Cell Transplantation 9Etoposide 9Azacitidine 9Methotrexate 8Decitabine 8Antilymphocyte Serum 8Specimen Handling 7Daunorubicin 7Biopsy 7fludarabine 6Tacrolimus 6Stem Cell Transplantation 6Cyclosporine 6decitabine and cedazuridine drug combination 5Melphalan 5Idarubicin 5Topotecan 4Rituximab 4Radiotherapy 4Prednisone 4Mitoxantrone 4Methylprednisolone 4Injections 4venetoclax 3sargramostim 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Myelodysplastic Syndromes × pevonedistat × Clear all
NCT03772925 2026-03-03

Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 1 Terminated
18 enrolled 19 charts
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03813147 2025-04-13

Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 1 Completed
12 enrolled 16 charts
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

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