Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 5OTHER 2NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Myeloid 2Other hematologic neoplasm 1

Conditions

Leukemia, Myeloid, Acute 6Myelodysplastic Syndromes 2Leukemia 2Thrombocytosis 1Thrombocythemia, Essential 1Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1Neoplasm, Residual 1Neoplasm Metastasis 1Myeloproliferative Disorders 1Mesothelioma 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Leukemia, Prolymphocytic, B-Cell 1Leukemia, Neutrophilic, Chronic 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hypereosinophilic Syndrome 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Cyclophosphamide 184fludarabine phosphate 162fludarabine 128Busulfan 116Tacrolimus 109Mycophenolic Acid 101Whole-Body Irradiation 97Antilymphocyte Serum 87Peripheral Blood Stem Cell Transplantation 84Azacitidine 82Melphalan 81Filgrastim 74Cytarabine 74Cyclosporine 72Methotrexate 64Decitabine 57Granulocyte Colony-Stimulating Factor 51Thiotepa 45Radiotherapy 41thymoglobulin 40Stem Cell Transplantation 40Cord Blood Stem Cell Transplantation 40venetoclax 39Clofarabine 35Sirolimus 30Methylprednisolone 30Specimen Handling 27Etoposide 24Alemtuzumab 24Biopsy 23

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Myelodysplastic Syndromes × pevonedistat × Clear all
NCT03862157 2026-03-11

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Active not recruiting
40 enrolled
MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Thrombocytosis, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hypereosinophilic Syndrome, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04712942 2023-08-21

Treatment of MDS/AML Patients With an Impending Hematological Relapse With AZA or ATA and Pevonedistat

University of Leipzig

Phase 2 Completed
14 enrolled
Myeloid

Myelodysplastic Syndromes, Neoplasm, Residual

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