Announcements Trials
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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Other neoplasm 1

Conditions

Primary Myelofibrosis 13Myeloproliferative Disorders 9Leukemia, Myeloid, Acute 8Thrombocythemia, Essential 6Polycythemia Vera 6Myelodysplastic Syndromes 5Leukemia 5Recurrence 3Neoplasms 3Lymphoma, T-Cell 3Graft vs Host Disease 3Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, T-Cell, Cutaneous 2Lymphoma 2Leukemia, Prolymphocytic, T-Cell 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Hematologic Neoplasms 2Uveal Melanoma 1Thalassemia 1Targeted Therapy 1Prostatic Neoplasms 1Preleukemia 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precancerous Conditions 1Neoplasms by Histologic Type 1Mycosis Fungoides 1Multiple Myeloma 1Mesothelioma 1Melanoma 1Lymphoma, T-Cell, Peripheral 1

Interventions

Specimen Handling 5Biopsy 5Whole-Body Irradiation 3Mycophenolic Acid 3Cyclosporine 3Cyclophosphamide 3Azacitidine 3venetoclax 2ruxolitinib 2fludarabine phosphate 2decitabine and cedazuridine drug combination 2Sirolimus 2Melphalan 2Injections 2Granulocyte Colony-Stimulating Factor 2Decitabine 2Busulfan 2veliparib 1tocilizumab 1tagraxofusp 1posaconazole 1peginterferon alfa-2b 1iadademstat 1gilteritinib 1fludarabine 1fedratinib 1axatilimab 1Tranexamic Acid 1Topotecan 1Tacrolimus 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Myelodysplastic-Myeloproliferative Diseases × ruxolitinib × 90 days × Clear all
NCT02158858 2026-06-04

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled 61 charts
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT04282187 2026-03-16

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

University of Washington

Phase 2 Recruiting
25 enrolled
MyeloidOther hematologic neoplasm

Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

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