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Phase

Phase 2 1Phase 1/2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 111Leukemia, Lymphocytic, Chronic, B-Cell 31Myelodysplastic Syndromes 25Leukemia, Biphenotypic, Acute 11Leukemia 11Recurrence 9Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Leukemia, Myelomonocytic, Chronic 8Burkitt Lymphoma 8Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 7Lymphoma, Mantle-Cell 7Lymphoma 7Hematologic Neoplasms 7Neoplasms 6Lymphoma, Large B-Cell, Diffuse 6Myeloproliferative Disorders 5Lymphoma, Non-Hodgkin 5Waldenstrom Macroglobulinemia 4Lymphoma, B-Cell, Marginal Zone 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Multiple Myeloma 3Lymphoma, Follicular 3Leukemia, Myeloid 3Sarcoma, Myeloid 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, B-Cell 2Immunoglobulin Light-chain Amyloidosis 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Blast Crisis 2Anemia, Refractory, with Excess of Blasts 2

Interventions

Specimen Handling 5Biopsy 5Azacitidine 3venetoclax 2decitabine and cedazuridine drug combination 2Whole-Body Irradiation 2Mycophenolic Acid 2Injections 2Granulocyte Colony-Stimulating Factor 2Decitabine 2Cyclosporine 2Cyclophosphamide 2veliparib 1tocilizumab 1tagraxofusp 1ruxolitinib 1posaconazole 1peginterferon alfa-2b 1iadademstat 1gilteritinib 1fludarabine phosphate 1fludarabine 1fedratinib 1axatilimab 1Tranexamic Acid 1Topotecan 1Sirolimus 1Rituximab 1Melphalan 1Idarubicin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Myelodysplastic-Myeloproliferative Diseases × venetoclax × 90 days × Clear all
NCT05600894 2026-05-13

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

Phase 2 Active not recruiting
132 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

NCT04140487 2026-04-16

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

M.D. Anderson Cancer Center

Phase 1/2 Recruiting
97 enrolled
MyeloidOther hematologic neoplasm

Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

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