Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 2

Conditions

Lymphoma 4Leukemia, Myeloid, Acute 4Leukemia 4Myelodysplastic Syndromes 3Lymphoma, Non-Hodgkin 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma, Follicular 3Lymphoma, B-Cell, Marginal Zone 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hodgkin Disease 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Myeloproliferative Disorders 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2Immunoblastic Lymphadenopathy 2Burkitt Lymphoma 2Anemia, Refractory, with Excess of Blasts 2Anemia, Refractory 2Stomach Neoplasms 1Sezary Syndrome 1Rectal Neoplasms 1Prostatic Neoplasms 1Neoplasms, Plasma Cell 1Mycosis Fungoides 1Multiple Myeloma 1

Interventions

Cyclophosphamide 45fludarabine phosphate 39Peripheral Blood Stem Cell Transplantation 36Busulfan 34Antilymphocyte Serum 26Tacrolimus 25Cyclosporine 25Methotrexate 23Filgrastim 23Mycophenolic Acid 22Radiotherapy 21Melphalan 17Etoposide 15Cytarabine 15Whole-Body Irradiation 14Methylprednisolone 13Cord Blood Stem Cell Transplantation 12Biopsy 9Azacitidine 9Specimen Handling 8ruxolitinib 7Sirolimus 7Flow Cytometry 7Cyclosporins 7Alemtuzumab 7Thiotepa 6Psychiatric Rehabilitation 6Decitabine 6sargramostim 5Rituximab 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Myelodysplastic-Myeloproliferative Diseases × 4-phenylbutyric acid × Clear all
NCT00006239 2017-09-29

Phenylbutyrate and Tretinoin in Treating Patients With Hematologic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT00004871 2010-03-10

Azacitidine Plus Phenylbutyrate in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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