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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1

Conditions

Triple Negative Breast Neoplasms 3Breast Neoplasms 3Anatomic Stage I Breast Cancer AJCC v8 2Uterine Cervical Neoplasms 1Thyroid Cancer, Papillary 1Stage I Mixed Cell Type Kidney Wilms Tumor 1Pleuropulmonary blastoma 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Myeloproliferative Disorders 1Myelodysplastic-Myeloproliferative Diseases 1Lymphedema 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Duodenal Neoplasms 1Carcinoma, Lobular 1Anatomic Stage III Breast Cancer AJCC v8 1Anatomic Stage II Breast Cancer AJCC v8 1Adenocarcinoma, Follicular 1

Interventions

Specimen Handling 3Azacitidine 3ruxolitinib 2Melphalan 2Cyclophosphamide 2Busulfan 2Biopsy 2venetoclax 1posaconazole 1onvansertib 1merphos 1gilteritinib 1fludarabine phosphate 1fludarabine 1fedratinib 1axatilimab 1Whole-Body Irradiation 1Watchful Waiting 1Tranexamic Acid 1Tacrolimus 1Succimer 1Stem Cell Transplantation 1Rituximab 1Positron-Emission Tomography 1Pentetic Acid 1Methotrexate 1Janus Kinase Inhibitors 1Injections 1Hyperbaric Oxygenation 1High-Energy Shock Waves 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Myelodysplastic-Myeloproliferative Diseases × High-Energy Shock Waves × Clear all
NCT05549661 2026-02-23

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Mayo Clinic

Phase 1 Recruiting
25 enrolled
MyeloidOther hematologic neoplasm

Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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