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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2

Conditions

Neoplasms 7Sarcoma 3Multiple Myeloma 3Leukemia 3Kidney Neoplasms 3Glioma 3Brain Neoplasms 3Waldenstrom Macroglobulinemia 2Sarcoma, Alveolar Soft Part 2Recurrence 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pancreatic Neoplasms 2Oligodendroglioma 2Myelodysplastic-Myeloproliferative Diseases 2Lymphoma 2Leukemia, Lymphocytic, Chronic, B-Cell 2Glioblastoma 2Colonic Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Astrocytoma 2Unspecified Adult Solid Tumor, Protocol Specific 1Solid Tumors 1Sarcoma, Synovial 1Sarcoma, Endometrial Stromal 1Rhabdomyosarcoma 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neurofibrosarcoma 1Myeloproliferative Disorders 1

Interventions

Cyclophosphamide 31fludarabine phosphate 25Peripheral Blood Stem Cell Transplantation 24Busulfan 22Antilymphocyte Serum 19Filgrastim 17Cyclosporine 16Tacrolimus 15Radiotherapy 15Methotrexate 14Mycophenolic Acid 12Etoposide 12Cytarabine 11Whole-Body Irradiation 10Methylprednisolone 10Melphalan 10Cyclosporins 6Cord Blood Stem Cell Transplantation 6sargramostim 5Psychiatric Rehabilitation 5Flow Cytometry 5ruxolitinib 4Thiotepa 4Thalidomide 4Early Intervention, Educational 4Azacitidine 4Alemtuzumab 4Tretinoin 3Sirolimus 3Polymerase Chain Reaction 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Myelodysplastic-Myeloproliferative Diseases × perifosine × Clear all
NCT00019656 2015-04-29

Perifosine in Treating Patients With Refractory Solid Tumors or Hematologic Cancer

National Cancer Institute (NCI)

Phase 1 Completed
LymphoidMyeloidOther hematologic neoplasm

Burkitt Lymphoma, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

NCT00301938 2013-09-30

7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes

National Cancer Institute (NCI)

Phase 1 Completed
30 enrolled
LymphoidMyeloidOther hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases

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