Announcements Trials
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Phase

Phase 2 1

Status

Terminated 1Recruiting 1Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 35Leukemia, Lymphocytic, Chronic, B-Cell 26Myelodysplastic Syndromes 11Lymphoma, Mantle-Cell 8Leukemia, Myelomonocytic, Chronic 8Neoplasms 7Burkitt Lymphoma 7Recurrence 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Multiple Myeloma 5Lymphoma, Non-Hodgkin 5Lymphoma, Follicular 5Lymphoma, B-Cell, Marginal Zone 5Lymphoma, B-Cell 5Myeloproliferative Disorders 4Lymphoma, Large B-Cell, Diffuse 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Leukemia, Biphenotypic, Acute 4Leukemia, B-Cell 4Waldenstrom Macroglobulinemia 3Leukemia 3Primary Myelofibrosis 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Lymphoma 2Hematologic Neoplasms 2Hematologic Diseases 2Thrombocytosis 1Thrombocythemia, Essential 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Polycythemia Vera 1

Interventions

fludarabine phosphate 2fludarabine 2Tacrolimus 2Specimen Handling 2Mycophenolic Acid 2Cyclophosphamide 2Busulfan 2Biopsy 2venetoclax 1veliparib 1tagraxofusp 1decitabine and cedazuridine drug combination 1Whole-Body Irradiation 1Topotecan 1Thiotepa 1Sirolimus 1Peripheral Blood Stem Cell Transplantation 1Methotrexate 1Melphalan 1Injections 1Idarubicin 1Granulocyte Colony-Stimulating Factor 1Etoposide 1Decitabine 1Cytarabine 1Cyclosporine 1Carboplatin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Active not recruiting × Myelodysplastic-Myeloproliferative Diseases × venetoclax × Clear all
NCT05600894 2026-05-13

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

National Cancer Institute (NCI)

Phase 2 Active not recruiting
132 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Myelodysplastic-Myeloproliferative Diseases

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