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Phase

Phase 1/2 1

Status

Terminated 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1CNS 1Breast 1

Conditions

Breast Neoplasms 193Carcinoma, Non-Small-Cell Lung 160Ovarian Neoplasms 96Lung Neoplasms 58Fallopian Tube Neoplasms 57Neoplasms 50Triple Negative Breast Neoplasms 36Neoplasm Metastasis 36Esophageal Neoplasms 22Carcinoma, Ovarian Epithelial 22Parkinson Disease 4, Autosomal Dominant Lewy Body 21Stomach Neoplasms 20Squamous Cell Carcinoma of Head and Neck 20Head and Neck Neoplasms 19Endometrial Neoplasms 19Adenocarcinoma of Lung 17Melanoma 15Breast Neoplasms, Male 15Urinary Bladder Neoplasms 13Carcinoma 12Uterine Cervical Neoplasms 11Recurrence 11Carcinoma, Squamous Cell 11Brenner Tumor 11Adenocarcinoma Of Esophagus 10Small Cell Lung Carcinoma 9Peritoneal Neoplasms 9Esophageal Squamous Cell Carcinoma 9Adenocarcinoma, Bronchiolo-Alveolar 9Prostatic Neoplasms 8

Interventions

fludarabine phosphate 43Whole-Body Irradiation 36Mycophenolic Acid 36Peripheral Blood Stem Cell Transplantation 31Cyclophosphamide 31Tacrolimus 28Busulfan 22Antilymphocyte Serum 21Cyclosporine 19fludarabine 17ruxolitinib 16Melphalan 16Methotrexate 15Cytarabine 12thymoglobulin 9Sirolimus 9Etoposide 9Granulocyte Colony-Stimulating Factor 8Filgrastim 8Cyclosporins 8Radiotherapy 7Cord Blood Stem Cell Transplantation 7Rituximab 6Alemtuzumab 6merphos 5Stem Cell Transplantation 5Flow Cytometry 5Azacitidine 5sargramostim 4ponatinib 4

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Has results × Myeloproliferative Disorders × Paclitaxel × Clear all
NCT02711137 2025-10-21

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Incyte Corporation

Phase 1/2 Terminated
137 enrolled 31 charts
BreastCNSGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Primary Myelofibrosis

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