Announcements Trials
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Phase

Phase 3 2

Status

Completed 1Active not recruiting 1

Sponsor Class

NETWORK 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 84Leukemia 49Lymphoma 21Burkitt Lymphoma 19Leukemia, Biphenotypic, Acute 14Leukemia, Myeloid, Acute 10Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 8Lymphoma, Extranodal NK-T-Cell 7Recurrence 6Lymphoma, Non-Hodgkin 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 4Myelodysplastic Syndromes 4Dendritic Cell Sarcoma, Interdigitating 4Neoplasm, Residual 3Down Syndrome 3Anemia, Refractory, with Excess of Blasts 3Myeloproliferative Disorders 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Monocytic, Acute 2Leukemia, Erythroblastic, Acute 2Leukemia, Eosinophilic, Acute 2Anemia, Refractory 2Thrombocytopenia 1Sarcoma, Myeloid 1Pancreatic Neoplasms 1Neutropenia 1Neoplasms 1Nasopharyngeal Carcinoma 1

Interventions

Cyclophosphamide 87fludarabine phosphate 86Peripheral Blood Stem Cell Transplantation 70Mycophenolic Acid 58Tacrolimus 57Busulfan 57Whole-Body Irradiation 55Antilymphocyte Serum 47Cyclosporine 46fludarabine 39Methotrexate 38Filgrastim 38Melphalan 32ruxolitinib 30Cytarabine 30Radiotherapy 27Azacitidine 23Etoposide 21Methylprednisolone 20Cord Blood Stem Cell Transplantation 18Specimen Handling 15Sirolimus 15Granulocyte Colony-Stimulating Factor 15Decitabine 15Cyclosporins 14Biopsy 14Alemtuzumab 14thymoglobulin 13venetoclax 11sargramostim 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Interventional × Myeloproliferative Disorders × Asparaginase × Clear all
NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT00003593 2013-06-27

Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome

Children's Oncology Group

Phase 3 Completed
254 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Juvenile, Myelodysplastic-Myeloproliferative Diseases

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