Announcements Trials
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Phase

Phase 3 2Phase 1/2 1

Status

Completed 1Active not recruiting 1

Sponsor Class

NIH 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Classical hematology 1

Conditions

Leukemia, Myeloid, Acute 22Leukemia 15Lymphoma 11Leukemia, Erythroblastic, Acute 8Prostatic Neoplasms 7Leukemia, Myelomonocytic, Acute 7Leukemia, Monocytic, Acute 7Leukemia, Megakaryoblastic, Acute 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, Large B-Cell, Diffuse 6Lymphoma, Follicular 6Myelodysplastic Syndromes 5Lymphoma, Non-Hodgkin 5Lymphoma, Large-Cell, Immunoblastic 5Anemia, Refractory, with Excess of Blasts 4Leukemia, Promyelocytic, Acute 3Congenital Abnormalities 3Breast Neoplasms 3Pain 2Neutropenia 2Myeloproliferative Disorders 2Leukemia, Myelomonocytic, Chronic 2Burkitt Lymphoma 2Sarcoma, Myeloid 1Recurrence 1Ovarian Neoplasms 1Neoplasms 1Neoplasm, Residual 1Myelodysplastic-Myeloproliferative Diseases 1Lymphoma, Large-Cell, Anaplastic 1

Interventions

ruxolitinib 6Peripheral Blood Stem Cell Transplantation 5Mycophenolic Acid 5Cytarabine 5fludarabine phosphate 4Whole-Body Irradiation 4Methotrexate 4Daunorubicin 4Thioguanine 3Tacrolimus 3Etoposide 3Early Intervention, Educational 3Cyclophosphamide 3ponatinib 2parsaclisib 2nilotinib 2merphos 2luspatercept 2fludarabine 2fedratinib 2anagrelide 2Tretinoin 2Therapeutics 2Psychiatric Rehabilitation 2Mitoxantrone 2Filgrastim 2Cyclosporins 2Cyclosporine 2Busulfan 2Asparaginase 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 3 × Myeloproliferative Disorders × Mitoxantrone × Clear all
NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT00005823 2013-12-18

Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

National Cancer Institute (NCI)

Phase 3 Completed
2,000 enrolled
Classical hematologyMyeloidOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Leukemia, Myelomonocytic, Acute, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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