Announcements Trials
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Phase

Phase 3 1Phase 2 1

Status

Completed 11Recruiting 2Active not recruiting 2Terminated 1

Sponsor Class

OTHER 24INDUSTRY 12NIH 2NETWORK 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Other neoplasm 1Lymphoid 1

Conditions

Breast Neoplasms 19Multiple Myeloma 16Prostatic Neoplasms 14Carcinoma, Non-Small-Cell Lung 12Neoplasms 10Precursor Cell Lymphoblastic Leukemia-Lymphoma 9Lymphoma 9Leukemia, Myeloid, Acute 7Lung Neoplasms 6Leukemia, Biphenotypic, Acute 6Squamous Cell Carcinoma of Head and Neck 5Neuroblastoma 5Medulloblastoma 5Lymphoma, Mantle-Cell 5Leukemia 5Hodgkin Disease 5Ependymoma 5Colorectal Neoplasms 5Oropharyngeal Neoplasms 4Neoplasm Metastasis 4Myelodysplastic Syndromes 4Leukemia, Myeloid, Chronic-Phase 4Leukemia, Myelogenous, Chronic, BCR-ABL Positive 4Burkitt Lymphoma 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Oligodendroglioma 3Melanoma 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hematologic Neoplasms 3Glioma 3

Interventions

fludarabine phosphate 1fludarabine 1asparaginase erwinia chrysanthemi recombinant 1Whole-Body Irradiation 1Thioguanine 1Tacrolimus 1Peripheral Blood Stem Cell Transplantation 1Patient Reported Outcome Measures 1Mycophenolic Acid 1Mitoxantrone 1Mesna 1Melphalan 1Leyk 1Etoposide 1Daunorubicin 1Cytarabine 1Cyclophosphamide 1Busulfan 1Asparaginase 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Active not recruiting × NETWORK × Myeloproliferative Disorders × Clear all
NCT06001385 2026-02-05

OPTIMIZE

Center for International Blood and Marrow Transplant Research

Phase 2 Active not recruiting
313 enrolled
LymphoidMyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Leukemia, Myeloid, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Children's Oncology Group

Phase 3 Active not recruiting
280 enrolled 13 charts
MyeloidOther hematologic neoplasm

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

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