Announcements Trials
Browse Landscape

Phase

Phase 1 3Phase 3 2Phase NA 1Phase 2 1

Status

Completed 6Active not recruiting 1

Sponsor Class

INDUSTRY 6OTHER 1

Study Type

Interventional 7

Sponsor

Cancer Type

Thoracic 4Tumor-Agnostic 1Head & Neck 1Dermatologic 1

Conditions

Carcinoma, Non-Small-Cell Lung 10Neoplasm Metastasis 7Melanoma 5Neoplasms 4Thyroid Neoplasms 3Neurofibromatosis 1 3Lung Neoplasms 3Uveal Melanoma 2Thyroid Cancer, Papillary 2Pancreatic Neoplasms 2Carcinoma, Hepatocellular 2Breast Neoplasms 2Triple Negative Breast Neoplasms 1Thyroid Diseases 1Thymoma 1Solid Tumours 1Solid Tumors 1Small Cell Lung Carcinoma 1Sarcoma 1Rectal Neoplasms 1Parkinson Disease 4, Autosomal Dominant Lewy Body 1Neuroma, Acoustic 1Neurofibrosarcoma 1Neurofibromatosis 2 1Neurofibroma, Plexiform 1Neuroblastoma 1Myelodysplastic-Myeloproliferative Diseases 1Myelodysplastic Syndromes 1Multiple Myeloma 1Meningioma 1

Interventions

Gemcitabine 43pembrolizumab 36Paclitaxel 36Nivolumab 31Docetaxel 29Capecitabine 29Bevacizumab 29Oxaliplatin 28Fluorouracil 28Cisplatin 26Leucovorin 24Cyclophosphamide 23Radiosurgery 20Irinotecan 20Carboplatin 20aldesleukin 19Cetuximab 19Interleukin-2 16fludarabine phosphate 15fludarabine 15Pemetrexed 15Trastuzumab 14Magnetic Resonance Spectroscopy 14Ipilimumab 14Fulvestrant 14130-nm albumin-bound paclitaxel 14Prednisone 13Everolimus 13Radiotherapy 12Panitumumab 12

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Has results × Neoplasm Metastasis × AZD 6244 × Clear all
NCT01933932 2025-11-19

SELECT-1

AstraZeneca

Phase 3 Active not recruiting
510 enrolled 16 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT01750281 2023-10-24

SELECT-2

AstraZeneca

Phase 2 Completed
212 enrolled 12 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03745989 2023-07-27

MK-8353-014

Merck Sharp & Dohme LLC

Phase 1 Completed
30 enrolled 19 charts
Tumor-Agnostic

Neoplasm Metastasis

NCT01809210 2018-03-13

SELECT-3

AstraZeneca

Phase 1 Completed
55 enrolled 21 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00970359 2017-04-12

Reacquisition of Radioactive Iodine (RAI) Uptake of RAI-Refractory Metastatic Thyroid Cancers by Pretreatment With the Selective MEK Inhibitor AZD6244

Memorial Sloan Kettering Cancer Center

Phase NA Completed
24 enrolled 8 charts
Head & Neck

Neoplasm Metastasis, Thyroid Diseases, Thyroid Neoplasms

NCT01974752 2017-01-05

SUMIT

AstraZeneca

Phase 3 Completed
152 enrolled 14 charts
Dermatologic

Uveal Melanoma, Neoplasm Metastasis

NCT01605916 2016-10-21

Investigate the Safety and Tolerability of AZD6244 Monotherapy or + Docetaxel in Japanese Patients With Advanced Solid Malignancies or Non-Small Cell Lung Cancer

AstraZeneca

Phase 1 Completed
33 enrolled 24 charts
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Neoplasms

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